Menopause and blood pressure.

Fatigue in Multiple Sclerosis

“…This method is supported by the construct validity of response latencies, easily obtainable through microcomputer testing. 4 This strategy may be implemented by monitoring speech hesitation and switching pauses in emotionally charged dialogues, reflecting properties of neuronal activity and firing. 2 Ernest H. Friedman, M.D.…”

Sleep and cardiac diseases amongst elderly people

“…DEAR SIR, the neurobiology of the association of poor sleep with an increase in angina pectoris and cardiac arrhythmias [ 11 is suggested by reports linking brainstem cardiovascular control, vasospasm and wakefulness to dopamine lateralized to the right hemisphere [ 2 ] . This hypothesis is supported by unilateral naris closure leading to a reduction of dopamine [3], and by profound effects on angina pectoris by attention to pauses during breathing induced by dopamine.…”

“…This hypothesis is supported by unilateral naris closure leading to a reduction of dopamine [3], and by profound effects on angina pectoris by attention to pauses during breathing induced by dopamine. These findings prompt the tailoring of behavioural interventions that may have the potential to reduce the risk for clinical events [2] by modifying respiratory rhythms in persons with sleep disturbances and cardiac arrhythmias [ 11. This method is supported by adaptation to stress manifested by slower, deeper breathing contributing to a 6.5-fold reduction in mortality [4].…”

“…Other epidemiological studies have used the Rose questionnaire, which requires positive answers to additional questions concerning the characteristics of the chest pain for a diagnosis. Even with these extra questions, the specificity is less than 100%: in a study of 244 patients (mean age 57 years) with chest pain referred for clinical exercise testing, who underwent thallium scanning, the specificity of the Rose questionnaire was 77% in males and 56% in females [2]. When 212 inpatients (mean age 62 years) with chest pain were investigated for coronary artery disease by angiography, the specificity of the Rose questionnaire was 75% in males and 84% in females [3].…”

Reply from the author:

“…3 These findings prompt the assessment of fatigue in the MS patient 1 by analyzing speech pauses on a time-base. 4…”