Menstrual disturbances in various thyroid diseases

Kakuno, Yoko; Amino, Nobuyuki; Kanoh, Maki; Kawai, Masahiro; Fujiwara, Masaru; M, Kimura; Kamitani, Ayako; Saya, Kaori; Shakuta, Reiko; Nitta, Sanae; Hayashida, Yasuko; Kudo, Takumi; Kubota, Sumihisa; Miyauchi, Akira

doi:10.1507/endocrj.k10e-216

Cited by 65 publications

(56 citation statements)

References 9 publications

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“…Thyroid dysfunction has been found to be associated with menstrual disturbances, however there are findings showing both high and low frequency of menstrual disorders in thyroid dysfunction [11]. Thyroid hormones affect menstrual cycle and both hyperthyroidism and hypothyroidism may result in menstrual disturbances [12].…”

Section: Discussionmentioning

confidence: 99%

Pattern of Thyroid Dysfunction in Women with Menstrual Disorders

Khatiwada

Gautam

et al. 2016

Ann. Clin. Chem. & Lab. Med.

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Section: Discussionmentioning

confidence: 99%

Pattern of Thyroid Dysfunction in Women with Menstrual Disorders

Khatiwada

Gautam

et al. 2016

Ann. Clin. Chem. & Lab. Med.

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“…Patients with severe hypothyroidism had a higher prevalence of menstrual disturbances (34.8%), than mild to moderate cases (10.2%). 4 In our study, most of the DUB patients were in the age group of 31-40 years (46%). This is in concurrence with the study done by Sangeetha et al, and Deshmukh et al, who observed that 42% and 44% of patients, respectively, belonged to age group of 31-40 years.…”

Section: Discussionmentioning

confidence: 49%

Clinical study of hypo/hyper thyroidism in dysfunctional uterine bleeding

Usharani

Shavi

2017

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONAbnormal uterine bleeding is a term used to describe any type of bleeding that does not fall within the normal range for amount, frequency, duration and cyclicity. Dysfunctional uterine bleeding (DUB) is defined as abnormal uterine bleeding in the absence of any palpable pelvic pathology and demonstrable extra genital causes. It occurs in 9-14% of women between menarche and menopause, significantly impacting quality of life and imposing financial burden.2 It is often difficult to identify the cause of abnormal bleeding even after a thorough history and physical examination. Thyroid hormones play a key role in the menstrual and reproductive function of women. Thyroid dysfunction is known to affect all aspects of reproductive function in the female.The spectrum of thyroid disorders is associated with a variety of changes in reproductive function ranging from delayed onset of puberty, anovulatory cycles and abnormally high fetal wastage. The most common manifestation of hyperthyroidism is oligomenorrhoea and anovulation, whereas hypothyroidism, even in its subclinical form, may result in excessive menstrual bleeding and severe blood loss.3 Treating thyroid ABSTRACT Background: Dysfunctional uterine bleeding is one of the most frequently encountered condition in gynaecological practice. Thyroid hormones play a key role in the menstrual and reproductive function of women and thus thyroid dysfunction results in menstrual disturbances. The objective is to study the prevalence of thyroid disorders in patients with dysfunctional uterine bleeding.Methods: This is a hospital based prospective observational study done in the department of Obstetrics and Gynaecology, Vijayanagara Institute of Medical Sciences, Ballari. The study period is from February 2016 to August 2016. In the study, 100 patients with dysfunctional uterine bleeding were included and evaluated for thyroid abnormality.Results: Among 100 patients with DUB, thyroid disorders were prevalent in 24 % of patients. Hypothyroidism was present in 22% and hyperthyroidism in 2% of the women with DUB. The commonest menstrual complaint associated with hypothyroidism was menorrhagia, seen in 54.54% of cases. In 2 patients with hyperthyroidism one each had menorrhagia and metropathia haemorrhagica. Conclusions: Thyroid dysfunction is one of the important cause for DUB. Hypothyroidism is more commonly associated with DUB than hyperthyroidism. Evaluation of thyroid status is important in all patients with DUB to avoid unnecessary surgical interventions.

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“…These differences can be explained by a more severe disease at diagnostic. Indeed, patients with severe hypothyroidism have a higher prevalence (34.8%) of menstrual disturbances than mild-moderate cases (10.2%) as reported in a study from Japan [6].…”

Section: Discussionmentioning

confidence: 77%