Mental and Physical Health Consequences of Alcohol Use in Women

Hill, Shirley Y.

doi:10.1007/0-306-47138-8_10

Cited by 20 publications

(17 citation statements)

References 60 publications

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“…Alcohol dependence (alcoholism) contributes to a variety of health problems including increased risk for cancers of the head and neck, hepatocellular carcinoma, cardiomyopathy, hypertension, coronary artery disease and stroke, liver disease including cirrhosis, fetal alcohol effects including Fetal Alcohol Syndrome, increased violence and accidents including those resulting from drunk driving [Hill, 1995a;Lieber, 1995]. Although lifetime prevalence in males appears to be higher than in females, the health and social consequences of alcohol use are quite substantial for women world wide [Hill, 1994[Hill, , 1995a.…”

Section: Introductionmentioning

confidence: 99%

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A genome wide search for alcoholism susceptibility genes

Hill

Shen

Zezza

et al. 2004

American J of Med Genetics Pt B

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115

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Alcoholism is currently one of the most serious public health problems in the US. Lifetime prevalence rates are relatively high with one in five men and one in 12 women meeting criteria for this condition. Identification of genetic loci conferring an increased susceptibility to developing alcohol dependence could strengthen prevention efforts by informing individuals of their risk before abusive drinking ensues. Families identified through a double proband methodology have provided an exceptional opportunity for gene-finding because of the increased recurrence risks seen in these sibships. A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4 cM and genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17.

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Section: Introductionmentioning

confidence: 99%

“…Although lifetime prevalence in males appears to be higher than in females, the health and social consequences of alcohol use are quite substantial for women world wide [Hill, 1994[Hill, , 1995a. The health costs have recently been estimated to be 184.6 billion, an increase of 25% since 1992 [Harwood, 2000].…”

Section: Introductionmentioning

confidence: 99%

A genome wide search for alcoholism susceptibility genes

Hill

Shen

Zezza

et al. 2004

American J of Med Genetics Pt B

Self Cite

115

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“…En muchos trabajos se menciona que las mujeres alcohólicas presentan patología hepática más severa que los hombres, así como mayor afectación cardiovascular, miopatía y osteoporosis, consumiendo menores cantidades de alcohol 12,13,21 . Se han propuesto algunas hipótesis para explicar esta mayor morbilidad del alcohol en el sexo femenino, aunque todas hacen hincapié en las diferencias farmacocinéticas que existen entre ambos géneros 22,23 .…”

Section: Discussionunclassified

“…Hay datos que ponen de manifiesto una relación directa entre cantidad consumida de alcohol y el cán-cer de mama 12,21 . Recientemente, Jiang et al 24 , en un estudio en el que valoraban la dosis ingerida de alcohol y los niveles de ácido fólico en una muestra de mujeres seguidas prospectivamente durante 16 años, comprobaron que existía una relación directa entre consumo excesivo de alcohol y bajos niveles de ácido fólico con la aparición de cánceres de mama y colon.…”

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Diferencias de género en la enfermedad alcohólica

Escribano¹,

Parra²

2007

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RESUMENEstudios epidemiológicos recientes señalan que el consumo de alcohol en la mujer ha aumentado en los últimos años, lo que nos hace pensar que en un futuro próximo habrá mayor número de mujeres que padezca alcoholismo. Además, su enfermedad presenta características diferenciales cuyo conocimiento es importante para iniciar el tratamiento lo más precozmente posible.El objetivo del presente estudio consiste en investigar las diferencias clínicas en los trastornos por uso de alcohol según el sexo de los pacientes. Se realizó en una muestra de 370 pacientes, 325 hombres (87,8%) y 45 mujeres (12,2%), cuya edad media era 42,83 y 44,60 años, respectivamente. Los pacientes fueron valorados mediante la entrevista estructurada Europasi y estudio analítico con perfil hepático y hemograma.Los resultados más destacados fueron: las mujeres iniciaban el consumo de alcohol significativamente más tarde que los hombres (19,61 y 16,90 años respectivamente; p<0,008), tenían significativamente más edad cuando el patrón de consumo era problemático (30,93 y 24,68 años; p<0,003), llevaban menos años de consumo (13,26 versus 17,85 años; p<0,02) y consumían menos gramos de alcohol (117,70 y 133,80 gr.; n.s.). En el Europasi las mujeres obtenían significativamente más puntuación que los hombres en la escala psiquiátrica (2,91 y 1,97 respectivamente; p<0,007) y éstos presentaban más problemas legales que aquellas (1,20 y 1,0; p<0,000). En las pruebas biológicas, los valores del enzima GGT eran más elevados en los hombres (137,51) que en las mujeres (96,7) aunque esta diferencia no era significativa y el valor del VCM era significativamente mayor en las mujeres (98,1 y 95,05; p<0,03). Otro hallazgo relevante fue que el porcentaje de mujeres que había acudido a dispositivos privados era mayor que el de hombres (15% versus 4,6%; p<0,01). ABSTRACTRecent epidemiological studies indicate that alcohol consumption in women has increased in the last few years, which suggests that alcoholism in women will also increase in the near future. Moreover, this disease shows differential characteristics in women, and knowledge of these characteristics is important so that treatment can begin as early as possible.The objective of the present study was to explore clinical differences in alcohol use disorders according to patients' gender. It was carried out with a sample of 370 patients, 325 men (87.8%) and 45 women (12.2%), with mean ages of 42.83 and 44.6 years, respectively. The patients were assessed through the Europasi interview and analytical studies with liver enzyme profiles and blood tests.The most notable results were: women began alcohol consumption significantly later than men (19.61 and 16.9 years, respectively; p< 0.008); they were significantly older than men when the consumption pattern became problematic (30.93 and 24.68 years, respectively; p< 0.003); they had been drinking for fewer years (13.26 versus 17.85 years; p< 0.02); and they drank fewer grams of alcohol (117.7 and 133.8 g., respectively; n.s.). Women scored significantly hi...

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