Mercury as a contact allergen

Wekkeli, M.; Hippmann, G.; Rosenkranz, Adam; Jarisch, Reinhart; Götz, M.

doi:10.1111/j.1600-0536.1990.tb01605.x

Cited by 14 publications

(4 citation statements)

References 14 publications

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“…The patch test response to GST appears to represent true contact allergy, rather than an irritant contact reaction (10,11). GST therefore seems to be a ''hidden allergen'', analogous to thimerosal (13), and a positive reaction may result from a previous subclinical sensitization. There is little structural similarity between thimerosal and GST, and the sulfur group in the 2 molecules is in a different oxidation state, so the reaction pattern does not appear to be due to a chemical similarity.…”

Section: Discussionmentioning

confidence: 97%

A controlled study of gold contact hypersensitivity

et al. 1998

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1203 patients attending for routine patch testing at 3 hospitals and 105 volunteers were tested with 0.5% and 0.05% gold sodium thiosulfate (GST). 38 patients (3.2%) and 5 volunteers (4.8%) had positive patch tests to GST. There were no significant differences between volunteers and patients with respect to age, sex, atopy or exposure to gold in dental restorations, jewellery or through occupation. There were no significant differences in prevalence of GST hypersensitivity in the 3 hospitals, or between patients and controls. This is the 1st controlled study of hypersensitivity to GST, and suggests that routine patch testing to gold is of limited clinical benefit.

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Section: Discussionmentioning

confidence: 97%

A controlled study of gold contact hypersensitivity

et al. 1998

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“…Ammoniated mercury and thimerosal are well-known contact sensitizers (1)(2)(3)(4). Systemic reactions to metallic mercury or ammoniated mercury (5-7), or to inhalation…”

Section: Commentmentioning

confidence: 99%

Periorbital contact dermatitis due to yellow mercuric oxide

Anonide¹,

Massone²

1996

Contact Dermatitis

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SHORT COMMUNICATIONS quite sporadic, caused respiratory distress right from the beginning, and finally produced active sensitization in a control (6), confirm its strong irritant and allergic potentials.Although sensitized to Dalbergia latifolia Roxb., whose main allergen is (R)-4-methoxy dalbergione, both patients reacted to the other dalbergiones, in particular to (R)-3,4-dimethoxy delbergione. As this specific allergen, the strongest known sensitizing dalbergione (7), occurs only in pao ferro (Machaerium scleroxyum Tul.), this response must be considered a cross-reaction.

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“…Mercury compounds are toxic and sensitise [5,6]. They are now rarely prescribed for topical use although organic mercurial chemicals still have a limited role as preservatives.…”

Section: Metalsmentioning

confidence: 99%