Merkel cell carcinoma of the upper extremity: Case report and an update

Abstract

Background: Merkel cell carcinoma is a rare but aggressive cutaneous primary small cell carcinoma. It is commonly seen in elderly affecting the head, neck, and extremities. Macroscopically may be difficult to distinguish MCC from other small cells neoplasms especially oat cell carcinoma of the lung.

Merkel cell carcinoma-A rare primary neuroendocrine skin tumor: Case report and discussion

“…[4] MCC most commonly occurs in the head and neck (50%), upper and lower limbs (35-40%), and less than 10% in the trunk. [5] Similarly, our patient also had MCC in the head and neck region. The epidemiological studies have revealed that large tumor size, male sex, truncal site, nodal/distant disease at presentation, and duration of disease before presentation are poor prognostic factors.…”

Merkel cell carcinoma of the hand: Case report and literature review

“…It has very rarely been described on the fingers or the hand, with only few case reports that we are aware of [3][4][5][6][7][8][9][10][11][12][13][14][15]16]. Because of its rarity and the small numbers of patients in clinical reports, management is not standardized.…”

“…Adjuvant radiation therapy has been clearly proven to provide benefit in local regional recurrence rate [3,5]. However, distant metastases and overall survival seem to be similar compared to those who did not receive radiation therapy [14]. Chemotherapy is recommended in case of distant metastases.…”

Merkel Cell Carcinoma of Left Groin: A Case Report and Literature Review

“…For an MCC metastatic disease (Stage III), radio- and chemotherapy are employed with a palliative intent [23]. MCC is predominantly a radio-sensitive malignancy, and utilization of radiation therapy is highly advised [24].…”