2018
DOI: 10.1111/bjd.16903
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Merkel cell polyomavirus is uncommon in New Zealand Merkel cell carcinomas

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Cited by 6 publications
(5 citation statements)
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“…In stark contrast, only 18–24% of Australian MCC and 23% of NZ MCC has been found to show MCPyV positivity . MCPyV‐positive tumours were generally located on the limbs whereas MCPyV‐negative tumours predominantly occurred on sun‐exposed areas . This supports the hypothesis of two distinct pathways contributing to MCC oncogenesis – one that is UV radiation‐mediated and another virally mediated pathway.…”
Section: Discussionmentioning
confidence: 63%
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“…In stark contrast, only 18–24% of Australian MCC and 23% of NZ MCC has been found to show MCPyV positivity . MCPyV‐positive tumours were generally located on the limbs whereas MCPyV‐negative tumours predominantly occurred on sun‐exposed areas . This supports the hypothesis of two distinct pathways contributing to MCC oncogenesis – one that is UV radiation‐mediated and another virally mediated pathway.…”
Section: Discussionmentioning
confidence: 63%
“…North American and European studies report MCPyV positivity in 64–100% of MCC cases . In stark contrast, only 18–24% of Australian MCC and 23% of NZ MCC has been found to show MCPyV positivity . MCPyV‐positive tumours were generally located on the limbs whereas MCPyV‐negative tumours predominantly occurred on sun‐exposed areas .…”
Section: Discussionmentioning
confidence: 97%
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“…MCPyV has been detected in 40–89% of MCCs in North American and European studies, and in 18–24% in Australian and New Zealand studies . To date, it is the only HPyV that has been shown to mediate tumorigenesis .…”
Section: Merkel Cell Polyomavirusmentioning
confidence: 99%
“…MCPyV has been detected in 40-89% of MCCs in North American and European studies, and in 18-24% in Australian and New Zealand studies. [14][15][16] To date, it is the only HPyV that has been shown to mediate tumorigenesis. 9 Two clades, or phylogenetic groups, of MCPyV DNA sequences have been characterized from different geographical regions.…”
Section: Merkel Cell Polyomavirusmentioning
confidence: 99%