Abstract:Epistaxis, or nasal bleeding, occurs in over half of the general population. It is caused by various etiological factors and affects both sexes and all age groups. The simplest treatment for a nosebleed is pinching of the ala nasi, referred to as the Hippocratic technique. In this study, we adopted different treatment protocols dependent on the severity of bleeding and assessed the etiology and efficacy of these modalities. This was a prospective study. We recruited 25 patients (24 adults and 1 child) who pres… Show more
“…Only 1 of the 25 patients had re-bleeding, and there were no additional complications. 18 Nasal packs are widely used in ENT practiceThere is no consensus regarding the duration of use for different nasal pack typesA longer duration of nasal pack use can cause various problemsAfter 48 hours, nasal pack use can damage nasal septum cartilageThis paper describes the first histopathological study published in English on the effects of nasal pack use over time…”
Objective
To determine histopathological changes in nasal mucosa associated with duration of nasal packing with Merocel tampons.
Methods
This study included 24 healthy rabbits, 6 rabbits per group. In group A, no tampon was applied. In group B, Merocel nasal tampons were applied and removed after 24 hours. In group C, the tampons were removed after 48 hours. In group D, the tampons were removed after 5 days. Specimens were obtained from the septum of each rabbit, including cartilage. Histopathological examination was performed.
Results
Significant differences were observed in terms of inflammatory infiltration and loss of cilia between groups A and B. Significant differences were also observed in terms of inflammatory infiltration, haematoma, cilia loss, epithelium dysplasia and cartilage degeneration between groups B and C. There were significant differences in terms of cilia loss, epithelium dysplasia and subepithelial fibrosis between groups C and D. Cartilage degeneration was mild in one animal in group B and in two animals in group C, and was moderate in four animals in group C.
Conclusion
It is recommended that Merocel nasal tampons are removed within 48 hours to preserve nasal mucosal function. Keeping the pack longer may cause cartilage degeneration and other complications.
“…Only 1 of the 25 patients had re-bleeding, and there were no additional complications. 18 Nasal packs are widely used in ENT practiceThere is no consensus regarding the duration of use for different nasal pack typesA longer duration of nasal pack use can cause various problemsAfter 48 hours, nasal pack use can damage nasal septum cartilageThis paper describes the first histopathological study published in English on the effects of nasal pack use over time…”
Objective
To determine histopathological changes in nasal mucosa associated with duration of nasal packing with Merocel tampons.
Methods
This study included 24 healthy rabbits, 6 rabbits per group. In group A, no tampon was applied. In group B, Merocel nasal tampons were applied and removed after 24 hours. In group C, the tampons were removed after 48 hours. In group D, the tampons were removed after 5 days. Specimens were obtained from the septum of each rabbit, including cartilage. Histopathological examination was performed.
Results
Significant differences were observed in terms of inflammatory infiltration and loss of cilia between groups A and B. Significant differences were also observed in terms of inflammatory infiltration, haematoma, cilia loss, epithelium dysplasia and cartilage degeneration between groups B and C. There were significant differences in terms of cilia loss, epithelium dysplasia and subepithelial fibrosis between groups C and D. Cartilage degeneration was mild in one animal in group B and in two animals in group C, and was moderate in four animals in group C.
Conclusion
It is recommended that Merocel nasal tampons are removed within 48 hours to preserve nasal mucosal function. Keeping the pack longer may cause cartilage degeneration and other complications.
“…In addition to this, nasal injury is common after nasal surgery, for which treatment must be started quickly. Several methods are available to treat epistaxis, among which electrocautery, vasoconstrictors, surgical procedures and nasal packing arise as the most popular [ 3 ].…”
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