Mesenchymal chondrosarcoma: An unusual lump in posterior maxilla

Abstract

International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. Mesenchymal chondrosarcoma is an uncommon, slow growing malignant tumor which is a rare variant of chondrosarcoma, having a predilection for the maxillofacial skeleton; less often involves the soft tissue sites in head and neck. Case Report: We report an unusual case of mesenchymal chondrosarcoma on posterior palate in a 45-year-old male, who was previously diagnosed as pleomorphic adenoma in private clinic. Conclusion: Mesenchymal chondrosarcoma shows varied clinical and radiographic features, with occurrence of this lesion in unusual locations like posterior region of jaws which may lead to error in clinical diagnosis and early treatment as it has high affinity for recurrence and delayed metastasis.

Mesenchymal Chondrosarcoma of the Maxillary Sinus: Reporting Case with Good Response to Radiotherapy

“…By definition, it is a locally aggressive or malignant group of cartilagenous matrix-producing neoplasms tumor and neoplastic osteoid should not be present according to the World Health Organization (WHO) [4]. Most of Chondrosarcoma occur in 3rd-6th decade of life [3], the present case also falls in 4th decade.…”

“…It has been described as an aggressive neoplasm with high tendency for recurrences and delayed metastasis [2]. They usually occur in middle aged individuals, but are rare in young patients, with predilection for anterior portion of maxilla [3]. The diagnosis is challenging and may be assisted by molecular pathologic techniques.…”

Mesenchymal chondrosarcoma of maxilla in paediatric patient

“…The differential diagnoses include small round blue cell neoplasms such as Ewing sarcoma or primitive neuroectodermal tumours (PNETs), dedifferentiated CS, small cell osteosarcoma and monophasic synovial sarcoma 6 19 20. The identification of chondroid matrix and undifferentiated mesenchymal cells is crucial for an accurate diagnosis.…”

“…The identification of chondroid matrix and undifferentiated mesenchymal cells is crucial for an accurate diagnosis. The cells in Ewing sarcoma contain cytoplasmic glycogen but lack cartilaginous component, and haemangiopericytoma-like pattern of MCS 6 20. PNET contains more pleomorphic small cells than in MCS with the presence of rosettes.…”