Mesenteric blood flow is related to disease activity and risk of relapse in ulcerative colitis: a prospective follow up study

Ludwig, D.; Wiener, S; Brüning, A; Schwarting, Karsten; Jantschek, Günter; Fellermann, Klaus; Stahl, Maren; Stange, Eduard F.

doi:10.1136/gut.45.4.546

Cited by 57 publications

(35 citation statements)

References 37 publications

(35 reference statements)

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“…The typical morphological signs in UC are thickening of the mucosa and thickening of hyperechogenic submucosa, which reflects edema of the submucosa. There is initial data that Doppler ultrasonography of the superior and inferior mesenteric arteries could be used to evaluate disease activity of UC as well as the risk for relapse [42,43,44]. However, this technique is only used in very few centers so far.…”

Section: Ultrasonography In Ucmentioning

confidence: 99%

“…By using power Doppler sonography, alterations in vascularization can easily be detected. As acute inflammatory activity within the bowel is usually associated with hyperemia and increased vascular flow, a qualitative and quantitative assessment of vascularization is particularly useful in determining the disease activity in children [42,59,62,63,64]. Differentiation of inflammatory from fibrotic strictures might be improved by using power Doppler ultrasonography [65] or by using CEUS [55] even though the current data are controversial.…”

Section: Ultrasonography In Pediatricsmentioning

confidence: 99%

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Bowel Ultrasonography in Inflammatory Bowel Disease

Kucharzik¹

2015

Dig Dis

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Background: The diagnosis of inflammatory bowel disease (IBD) is based on a combination of endoscopic, clinical and biochemical investigations as well as cross-sectional imaging. The applications of cross-sectional imaging in IBD are manifold. Ultrasonography has emerged as an important imaging modality in the diagnosis of Crohn's disease (CD) as well as for monitoring disease progression and in the therapeutic response to CD and ulcerative colitis (UC). Key Messages: Ultrasonography is non-invasive, radiation free, cheap, easy to use and well tolerated and accepted by patients. Bowel ultrasonography can be used for the primary diagnosis of CD as it has a similar sensitivity and specificity like that of MRI and CT, particularly in the case of CD. Ultrasonography can also be used to monitor treatment response to therapy and to detect disease recurrence of CD as well as UC. In CD, ultrasonography can also be used to detect complications such as strictures as well as extramural complications, including abscesses and fistulas. Contrast-enhanced ultrasonography is a useful tool that might be helpful to detect certain indications in CD, in particular the differentiation between abscesses and inflammation. Conclusion: A variety of advantages of bowel ultrasonography over other imaging modalities suggest the more frequent use of this method to manage IBD patients in daily practice. Bowel ultrasonography should be a standard tool in IBD centers.

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Section: Ultrasonography In Ucmentioning

confidence: 99%

Section: Ultrasonography In Pediatricsmentioning

confidence: 99%

Bowel Ultrasonography in Inflammatory Bowel Disease

Kucharzik¹

2015

Dig Dis

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“…It has been pointed out that the US aspect of the intestine after 3 months of therapy can predict the outcome of UC at 15 months, as accurately as endoscopic scores [89,92]. Also, some studies suggest that Doppler US of the superior and inferior mesenteric arteries can be used for assessing the disease severity and the relapsing risk [93,94].…”

Section: Ulcerative Colitismentioning

confidence: 99%

The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Marin

Tribus

Fierbinţeanu-Braticevici

2018

Med Ultrason

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Inflammatory bowel diseases have an important impact upon the economic and social status due to their increasing incidence and prevalence, often affecting young people. At the moment, the therapeutic goal goes beyond the improvement of symptoms and laboratory parameters, being represented by endoscopic mucosal healing, changing the disease’s natural history. Even though endoscopy is the gold standard for the assessment of mucosal healing, it is an invasive maneuver and it lacks good repeatability. These patients require frequent evaluation; therefore, interest for noninvasive techniques has risen.As a consequence, the importance of intestinal ultrasound has increased lately and recent studies support its use to assess the degree of inflammation, to differentiate between remission and relapse, to monitor therapy response and guide treatment, to evaluate prognosis, and to diagnose complications. Another promising noninvasive imagistic technique is elastography which has gained interest because of its capacity to discriminate between inflammatory and fibrotic tissue, taking into account the different therapeutic options for the fibrotic strictures compared to inflammatory processes. This review summarizes the actual recommendations regarding the use of intestinal ultrasound and elastographic techniques for the diagnosis and monitoring of inflammatory bowel diseases.

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“…In späteren Studien zeigten Dopplermessungen der Mesenterialarterien keinen statistisch signifikanten Unterschied zwischen Patienten mit einem aktiven und einem inaktiven Morbus Crohn [Miao et al 2002]. Die Bedeutung der Dopplermessungen der Arteria mesenterica superior und inferior für die Beurteilung der Krankheitsaktivität wird kontrovers beurteilt [Ludwig et al 1999, 2004, Yekeler et al 2005], eine Bestimmung der entzündlichen Aktivität einzelner Darmsegmente kann jedoch in keinem Fall von Messungen an den großen Viszeralarterien erwartet werden.…”

Section: Dopplershifts Sowie Ausgeprägter Inter-und Intraindividuelleunclassified

Prospektiver Vergleich von Power-Dopplersonographie und Ileokoloskopie in der Aktivitätsbewertung bei Patienten mit Morbus Crohn

Neye¹

2015

Z Gastroenterol

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Mesenteric blood flow is related to disease activity and risk of relapse in ulcerative colitis: a prospective follow up study

Abstract: (Gut 1999;45:546-552)

Cited by 57 publications

References 37 publications

Bowel Ultrasonography in Inflammatory Bowel Disease

Bowel Ultrasonography in Inflammatory Bowel Disease

The importance of intestinal ultrasound and elastographic techniques in inflammatory bowel diseases

Prospektiver Vergleich von Power-Dopplersonographie und Ileokoloskopie in der Aktivitätsbewertung bei Patienten mit Morbus Crohn

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