Mesoporous Silica and Organosilica Nanomaterials as UV-Blocking Agents

Abstract

Mesoporous silica nanoparticles (MSN) and periodic mesoporous organosilica nanoparticles containing bridging benzene (PMOBTB) and ethane (PMOBTE) moieties are synthesized, characterized, and evaluated for application in skin protection from UVA/UVB sun irradiation. Furthermore, the influence of surface functionalization with chelating 3-(2-aminoethylamino)propylsilane and Zn ions on the UV-blocking ability of MSN is evaluated, along with the photostability and capability of the synthesized nanomaterials to carry avobenzone, a known UV-absorbing agent. The obtained results reveal promising characteristics of MSN and PMO materials with regard to their potential for sunscreen applications, which could be beneficial in terms of alleviating concerns about health and environmental hazards of sunscreen ingredients.

Facile development of photochromic cellulose acetate transparent nanocomposite film immobilized with lanthanide‐doped pigment: ultraviolet blocking, superhydrophobic, and antimicrobial activity

“…[ 49,50 ] CA‐based nanocomposites exhibit high sensitivity and faster response times due to their high surface area and high porosity. [ 51 ] Nanomaterials have been utilized in order to impart CA films with novel properties, such as photoactivity, [ 52 ] flame‐retardancy, [ 53,54 ] magnetic and catalytic activity, [ 55,56 ] UV blocking, [ 57 ] antimicrobial properties, [ 58 ] bioactivity, [ 59 ] and gas permeability. [ 60 ] A significant property of nanomaterial utilization is their capability to maintain transparency of CA films.…”

Dealing with Skin and Blood-Brain Barriers: The Unconventional Challenges of Mesoporous Silica Nanoparticles

“…MSNs possess all the characteristics of an efficient DDS [2], so they are emerging as good candidates to become reliable vehicles in a variety of applications [5,33,34].…”

“…An example are the inorganic ingredients of sunscreens, used to preserve skin from UV radiation. In this context, silica NPs offer solutions which are highly compatible with human health and the environment [33].…”

“…Knežević et al [33] emphasized the high potential of functionalized silica-based nanomaterials (healthier and environmentally friendly) for application in skin protection from UV irradiation. Tolbert et al have designed hybrid organic/inorganic silica particles, encapsulating organic sunscreens in silica NPs, in order to reduce their phototoxicity and degradation [59].…”

Functionalized Periodic Mesoporous Organosilica Nanoparticles for Loading and Delivery of Suramin

“…PMO nanoparticles are distinguished as highly promising for drug delivery and other applications [9][10][11][12][13], predominantly due to their high surface area, possibilities for versatile surface modifications, stimuli-responsive degradability and high biocompatibility. Previously, we demonstrated the potential of PMO nanoparticles for efficient cancer therapy and diagnostics [14,15], as well as for skin protection from UV irradiation [16]. Mesoporus silica nanoparticles (MSN) are more studied structural analogues of PMO for cancer therapy and plethora of other applications [17][18][19][20][21].…”