Mesoscale mobile robots for gastrointestinal minimally invasive surgery (MIS)

Gorlewicz, Jenna L.; Webster, Robert J.; Valdastri, Pietro

doi:10.1533/9780857097392.224

Cited by 3 publications

(4 citation statements)

References 103 publications

(80 reference statements)

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“…In the oesophagus, ingested substance has very fast transit time i.e 10s so a dual camera system and faster image capture speed is Capsule endoscope for oesophagus required. The marketed capsule is PillCam ESO and has a frame rate of 14 frames/s [3,4].…”

Section: Capsule Robots For Endoscopymentioning

confidence: 99%

“…Capsules can be longer in length compared to other capsule endoscopes. The marketed capsule is PillCam colon with the frame rate 4-35 frames/s [4].…”

Section: Capsule Endoscope For Small Intestinementioning

confidence: 99%

“…The main aim of this system is to capture clear images of the GI tract with high resolution. It consists of a lens, LED, vision sensor and a chip to compress the images [4]. Earlier CCD was used but now CMOS has replaced it.…”

Section: Materials For Fabrication [7]mentioning

confidence: 99%

“…Power supply [10,11] Segmentation and peristalsis helps a WCE to move through the GI tract. In segmentation, alternate contraction of different rings of circular muscle occurs and in peristalsis, sequential contraction and relaxation of continuous rings of smooth muscles occur [4].…”

Section: Measurement Of Transmissionmentioning

confidence: 99%

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Capsule Robot: A Theranostic Approach

Shanbhag¹,

Gawade²,

Patil³

et al. 2019

Act Scie Pharma

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The rising demand for non invasive methodology for diagnosis and treatment led to the invention of capsule robots. The submarine type capsules which travel inside the body were used for endoscopy with a chief role in targeted drug delivery systems. Traditional endoscopy involves usage of a pliable endoscope which is inserted into the body cavity by a doctor for medical imaging of a diseased part inside the body. It has been successful in aiding physicians for viewing gastrointestinal tract, respiratory tract, urinary tract and other cavities in the human body. But these endoscopes have drawbacks such as risk of infection, forming perforations and tear. Endoscopic capsules are non invasive, painless and more secure to be employed for long term screening purposes [1]. The main advantage is that they can access difficult body parts that were not possible to reach before with standard endoscopy such as small intestine [2]. Wireless capsule endoscopes with advanced functionalities such as biopsy or drug delivery are highly advisable. For the release of drugs at different sections of GIT in Increasing development in healthcare systems and availability of efficient miniaturized components or systems that are economic has led to profound scope for research in many new fields. Capsule robot was one such fictional idea that turned into factual reality because of use of applicative miniaturized components. Initially capsule robots were developed for endoscopic applications. These travel inside the gastrointestinal tract and thus capture images of the gastrointestinal tract and related areas. Later, capsule robots were developed to be used as the unique tool to construct micron and sub-micron sized drug delivery systems for target delivery and treatment. This article highlights on various aspects of capsule robots in diagnosis and therapy of various disorders and diseases, together called theranostic approach in drug delivery systems.

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Section: Capsule Robots For Endoscopymentioning

confidence: 99%

“…Capsules can be longer in length compared to other capsule endoscopes. The marketed capsule is PillCam colon with the frame rate 4-35 frames/s [4].…”

Section: Capsule Endoscope For Small Intestinementioning

confidence: 99%

Section: Materials For Fabrication [7]mentioning

confidence: 99%

Section: Measurement Of Transmissionmentioning

confidence: 99%

See 2 more Smart Citations

Capsule Robot: A Theranostic Approach

Shanbhag¹,

Gawade²,

Patil³

et al. 2019

Act Scie Pharma

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Design, modeling and control of a SMA-actuated biomimetic robot with novel functional skin

Alcaide

Pearson

Rentschler

2017

2017 IEEE International Conference on Robotics and Automation (ICRA)

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Acoustic Sensing and Ultrasonic Drug Delivery in Multimodal Theranostic Capsule Endoscopy

Stewart

Qiu

Lay

et al. 2017

Sensors

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Video capsule endoscopy (VCE) is now a clinically accepted diagnostic modality in which miniaturized technology, an on-board power supply and wireless telemetry stand as technological foundations for other capsule endoscopy (CE) devices. However, VCE does not provide therapeutic functionality, and research towards therapeutic CE (TCE) has been limited. In this paper, a route towards viable TCE is proposed, based on multiple CE devices including important acoustic sensing and drug delivery components. In this approach, an initial multimodal diagnostic device with high-frequency quantitative microultrasound that complements video imaging allows surface and subsurface visualization and computer-assisted diagnosis. Using focused ultrasound (US) to mark sites of pathology with exogenous fluorescent agents permits follow-up with another device to provide therapy. This is based on an US-mediated targeted drug delivery system with fluorescence imaging guidance. An additional device may then be utilized for treatment verification and monitoring, exploiting the minimally invasive nature of CE. While such a theranostic patient pathway for gastrointestinal treatment is presently incomplete, the description in this paper of previous research and work under way to realize further components for the proposed pathway suggests it is feasible and provides a framework around which to structure further work.

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Mesoscale mobile robots for gastrointestinal minimally invasive surgery (MIS)

Cited by 3 publications

References 103 publications

Capsule Robot: A Theranostic Approach

Capsule Robot: A Theranostic Approach

Design, modeling and control of a SMA-actuated biomimetic robot with novel functional skin

Acoustic Sensing and Ultrasonic Drug Delivery in Multimodal Theranostic Capsule Endoscopy

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