Messung der Intensitätsverteilung von YAG-Laserstrahlung im Gewebe

Bödecker, V.; Rudolph, Michael L.; Grotelüschen, Bernd

doi:10.1515/bmte.1974.19.4.160

Cited by 8 publications

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“…These are two critical processes which deter mine the pattern of heating. The thermal effects of laser radiation caused by the interaction of infrared laser light with biological tissue have been studied widely [1][2][3][4]. The different biological effects of the various types of laser are explained by the very narrow range of laser light at defined regions of the spectrum.…”

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confidence: 99%

Dosimetry of the Neodymium-YAG Laser in Urological Applications

Pensel¹

1986

Eur Urol

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confidence: 99%

Dosimetry of the Neodymium-YAG Laser in Urological Applications

Pensel¹

1986

Eur Urol

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“…Hepatic surgery, by means of carbon dioxide (CO2), has been performed in monkeys [17,22], in pigs [14], in rats [12], in dogs [4,8,13], and also in man [7,11,20]. Surgical capabilities of Nd YAG and argon laser have been published in a few detailed experimental papers [1,6,9,10,14,16].…”

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confidence: 99%

Experimental comparative study on morphological effects of different lasers on the liver

et al. 1982

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Three types of laser radiation were compared as to their capabilities in hepatic surgery using 17 New Zealand rabbits. In four animals, subtotal scalpel lobectomy was performed, the hepatic pedicle being clamped. Hemostasis is obtained by means of argon or Nd YAG laser as long as the internal diameter of the vessels encountered is less than 4.5 mm. Nd YAG laser requires a power output four times higher than argon laser to obtain hemostasis. In six animals limited resection was performed by means of Nd YAG and CO2 lasers. CO2 radiation supplied insufficient hemostasis whenever the vessel diameter was more than 1 mm despite an excellent cutting power. Nd YAG radiation created an important necrosis zone due to thermal diffusion. In seven animals various focal hepatic lesions produced by the three types of laser were compared. Argon laser induced superficial and regularly round lesion, Nd YAG laser deeper, cauliflower-like lesions with thermal diffusion following especially vessels. Veins presented thrombosis of their blood content and coagulation necrosis of their wall. The amount of glycogenic granulation decreased. The CO2 laser induced very sharp punctual lesion without necrosis. Electron-microscopic sections revealed faint shadowy liver cells closet to the thermal source and bubbled mitochondria containing disrupted critea around the lesion. In later lesions Nd YAG laser produced more extensive fibrosis than argon or CO2 laser. After first clinical trials we believe that laser irradiation is actually an adjuvant safety factor in current hepatic surgery, whereas the Nd YAG laser could be of real interest in metastatic carcinoma destruction in liver.

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Hepatic Resection With an Nd.YAG Laser in Pig

Godlewski

Ginoves

et al. 1983

Lasers Surg Med

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Eleven hepatic resections were performed by means of a divergent Nd:YAG laser. The beam was transmitted through a fiberoptic delivery system without any handpiece. The shortest resection time and most limited ischemic damage (4 mm) were obtained with 80-W power shoots and a low divergent beam (4 degrees 2 for full angle). The hemostatic effects of the Nd:YAG controlled bleeding from veins of up to 4.5 mm in diameter, and parenchymatic oozing from the cut edge minimized blood loss. Histological examination revealed the importance of cellular deterioration in the ischemic layer, while electron microscopy showed selective destruction of cell organelles and protein denaturation. Marked elevation of hepatic serum enzymes suggests a high degree of cellular damage. Postoperative examinations confirmed an uncomplicated healing process. Finally, the use of a flexible fiberoptic enables easy surgical manipulation.

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Messung der Intensitätsverteilung von YAG-Laserstrahlung im Gewebe

Cited by 8 publications

References 0 publications

Dosimetry of the Neodymium-YAG Laser in Urological Applications

Dosimetry of the Neodymium-YAG Laser in Urological Applications

Experimental comparative study on morphological effects of different lasers on the liver

Hepatic Resection With an Nd.YAG Laser in Pig

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