Meta-analysis of adjunctive non-NK1 receptor antagonist medications for the control of acute and delayed chemotherapy-induced nausea and vomiting

Santana, Thaiana Aragão; Trufelli, Damila Cristina; Matos, Leandro Luongo de; Cruz, Felipe Melo; Giglio, Auro del

doi:10.1007/s00520-014-2392-z

Cited by 10 publications

(12 citation statements)

References 32 publications

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“…A wide range of drugs have been associated with central emetic side effects and secondary effects due to gastric irritation [ 8 ]. Among the drugs with central emetic effects are opiate analgesics [ 85 ] and chemotherapeutics agents [ 86 ]. Other drugs can induce vomiting secondary to gastric irritation, such as aspirin, diuretics, and alcohol [ 5 ].…”

Section: Side Effect Of Drugsmentioning

confidence: 99%

Causes of Dental Erosion: Intrinsic Factors

Scaramucci

Carvalho

Hara

et al. 2015

Dental Erosion and Its Clinical Management

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The consequences of the severe wear caused by intrinsic erosion, in addition to the high cost and complexity of the treatment to restore severely worn dentition, support the importance of early diagnosis and implementation of preventive/therapeutic measures. Dental professionals must be aware of the signs and symptoms of the disease, as well as all the conditions that may lead to the presence of gastric juice in the mouth, so they can make the referral to the appropriate medical specialist. In this chapter, the main clinical conditions associated with intrinsic erosion are presented and its clinical signs and symptoms discussed from a clinical perspective.

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Section: Side Effect Of Drugsmentioning

confidence: 99%

Causes of Dental Erosion: Intrinsic Factors

Scaramucci

Carvalho

Hara

et al. 2015

Dental Erosion and Its Clinical Management

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“…18,20 This mismatch between patient and carer interest and clinician reluctance is likely to be reflected in the low levels of prescribing to date in Australia, 19 as well as media reporting of patient dissatisfaction with clinician responses. [2][3][4][5][6] Despite little scientific evidence for supporting cannabis use as a control or cure for cancer, one-quarter (25%) of patient and/or carers were seeking information or requesting medicinal cannabis for this intent. 17 We did not collect data as to the reasons for selfsourced cannabis use versus medicinal cannabis use, although this may be related to cost, clinician reluctance to prescribe or preparations available.…”

Section: Brief Communicationsmentioning

confidence: 99%

“…[2][3][4][5][6] Research is being undertaken in multiple sites in Australia, including clinical trials, in order to address limitations in the evidence to date. Currently, there is low to moderate quality evidence to suggest medicinal cannabis may improve the experience of pain, wasting, vomiting, or nausea for people with cancer.…”

mentioning

confidence: 99%

“…Currently, there is low to moderate quality evidence to suggest medicinal cannabis may improve the experience of pain, wasting, vomiting, or nausea for people with cancer. [2][3][4][5][6] Research is being undertaken in multiple sites in Australia, including clinical trials, in order to address limitations in the evidence to date. [7][8][9][10] Despite this limited evidence, 11,12 there have been recent regulatory changes in Australia to allow for the prescribing of medicinal cannabis products for patients, including those with cancer.…”

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confidence: 99%

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Who is asking about medicinal cannabis in palliative care?

Panozzo

Collins

et al. 2020

Internal Medicine Journal

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Following legislative changes in the availability and prescribing of medicinal cannabis in Australia, we sought to understand prospectively the nature of information seeking and requests for medicinal cannabis in consultations between palliative care clinicians and patients with cancer. The 104 discussions were overwhelmingly initiated by patients and carers (93%) and were for a variety of symptoms, reflecting high levels of patient interest in the use of medicinal cannabis in cancer. AbstractPsittacosis is a human systemic disease caused by infection with Chlamydia psittaci. Shortly after reports emerged of a global pandemic associated with contact with imported parrots, Australian researchers including Macfarlane Burnet and others demonstrated that C. psittaci was widespread in Australian parrots. Australian cases over the last two decades have revealed that environmental exposure and contact with infected horses are also risk factors in an increasingly complicated epidemiological picture for this zoonotic disease.

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“…As principais diretrizes não recomendam seu uso nesse momento. Em alguns casos, o dronabinol pode ser considerado no tratamento da êmese refratária, e as doses recomendadas são de 5 a 10 mg/m 2 a cada 3 a 4 horas, por via oral 5,6,14,15 .…”

Section: Métodos|unclassified

Avaliação de náusea e êmese em pacientes sob quimioterapia em uma Unidade de Alta Complexidade Saúde de Vitória da Conquista/BA

Queiroga¹,

Ferraz²,

Gama³

et al. 2018

RBPS

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RESUMO| Introdução: Náusea e êmese constituem importantes reações adversas da quimioterapia antineoplásica. O tratamento antiemético adequado e o acompanhamento individualizado são fundamentais para o sucesso do tratamento. Objetivo: Avaliar o tratamento antiemético de pacientes em uso de quimioterápicos com alto potencial emetogênico assistidos pelo Sistema Único de Saúde no município de Vitória da Conquista/BA. Métodos: Estudo de caráter prospectivo com coleta de dados de prontuário e aplicação de questionário semiestruturado adaptado do Multinational Association of Supportive Care in Cancer em indivíduos maiores de 18 anos em uso de quimioterápicos de alto potencial emetogênico e em realização de terapia antiemética. Resultados: No grupo estudado, 57%(33) dos pacientes apresentaram náuseas, sendo (13) 39,6% de forma aguda; e, (15) 46,5%, náusea crônica. A êmese acometeu 34,4% (20) dos pacientes, sendo 20,7% de forma aguda; e, 24,1%, crônica. O protocolo antiemético utilizado em 81% dos pacientes foi ondansetrona 8 mg e dexametasona 10 mg. Segundo diretrizes internacionais, o protocolo antiemético poderia ser melhor otimizado. Conclusão: A terapia antiemética aplicada não foi eficaz no manejo de reações adversas a quimioterapia antineoplásica no grupo estudado. A subutilização dos antieméticos pode ter contribuído para a falta de controle efetivo das náuseas e vômitos. Este trabalho alerta para a necessidade de maior atenção no tratamento das reações adversas da quimioterapia, especialmente das náuseas e êmese. A diminuição desses eventos contribui para melhora da qualidade de vida dos pacientes e também para a menor permanência hospitalar.

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Meta-analysis of adjunctive non-NK1 receptor antagonist medications for the control of acute and delayed chemotherapy-induced nausea and vomiting

Abstract: We conclude that adjunctive non-NK1 antagonist medications may be useful for CINV control. Prospective randomized studies incorporating these low-cost medications into new regimens combining 5-HT3 and NK1 antagonists may be warranted.

Cited by 10 publications

References 32 publications

Causes of Dental Erosion: Intrinsic Factors

Causes of Dental Erosion: Intrinsic Factors

Who is asking about medicinal cannabis in palliative care?

Avaliação de náusea e êmese em pacientes sob quimioterapia em uma Unidade de Alta Complexidade Saúde de Vitória da Conquista/BA

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