Meta-analysis of clinical studies on the efficacy of flavonoids in viral and viral-bacterial diseases in children

Крамарев, С А; Grinevich, A.I.; Tonkovid, O.B.; Vygovskaya, O.V.

doi:10.15574/sp.2014.61.39

Cited by 2 publications

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“…В Україні щорічно на ГРІ хворіє 10-14 млн осіб, що становить 25-30% загальної та близько 75-90% інфекційної захворюваності [6]. Експерти Всесвітньої організації охорони здо ров'я (ВООЗ) зазначають, що ця найпоширені ша в людській популяції група захворювань останніми роками має постійну тенденцію до збільшення.…”

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Acute respiratory infections in children: current trends in antiviral therapy

Andrikevych¹

2021

MPU

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The aim is тto study the clinical efficacy of Flavovir® in the treatment of acute respiratory viral infections (ARVI) in young children. Materials and methods. The study included 60 young children who received outpatient treatment at the primary health care centers of the Vinnytsia region in the period from 2019 to 2021. The inclusion criteria for the study were ARVI and age аfrom 1 month to 3 years; exclusion criteria were еaggravated premorbid background (immunodeficiency diseases, congenital malformations, etc.), the use of other antiviral drugs, influenza vaccination. According to this aim the children are divided into two groups. The first group consisted of 30 children with ARVI who received Flavovir® (Research and Production Company "Ecopharm" Ltd, Ukraine) in combination with symptomatic therapy. The second group consisted of 30 patients with ARVI who received only symptomatic therapy. The distribution of patients into groups was carried out randomly. The groups were representative for age, sex, structure and severity of disease. Results. During the study the drug Flavovir® showed an effective antiviral effect in the treatment of acute respiratory viral infections in young children. In ase of the introduction of Flavovir® in the treatment regimen of the examined patients, a positive dynamics of clinical disease was noted: the intoxication syndrome disappeared three times faster (Group I — duration on average 3.4±0.2 days; Group II — 10.4±0.6 days , p<0.05), catarrhal syndrome disappeared approximately two times faster (group I — duration on average 4.5±0.4 days; II group — 9.6±0.7 days, p<0.05); нthere was a reduction in the recovery time by almost two times (group I — on average 5.81±0.5 days, II group — 11.8±0.6 days, p<0.05). The drug is well tolerated by patients and safe for children. Conclusions. The results obtained allow to recommend Flavovir® in age-specific doses for the etiotropic therapy of modern acute respiratory viral infections in young children, taking into account the direct antiviral effect of the drug. The study was carried out in accordance with the principles of the Declaration of Helsinki. The informed consent of the parents of the children was obtained for the research. The author declares no conflicts of interest. Key words: children, treatment, acute respiratory viral diseases, Flavovir.

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Acute respiratory infections in children: current trends in antiviral therapy

Andrikevych¹

2021

MPU

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E-Book Reading Applications – Innovative Technology as a Response to Growing Consumer Preferences and Its Implications for Tourism

Meštrović¹,

Marot²

2017

Tourism in Southern and Eastern Europe

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Purpose -This paper aims to explore factors influencing users' attitudes and intention to use mobile e-book reading applications (Apps) on smartphones and tablets, as well as their perceptions of Apps' potential for enhancing tourists' experiences as an added value of Croatian tourist offer. Design/methodology/approach -The study explores the relationships between respondents' digital devices ownership, their general information technology (IT) and e-books usage habits, the factors influencing their attitudes and intention to use a free mobile e-book reading Apps and to determine their perceptions on their potential added value. To achieve the aim of the study, authors extended the Technology Adoption Model with the Innovation Diffusion Theory, Theory of Planned Behaviour, convenience, availability and perception of mobile e-book reading Apps as a value-added service. The quantitative data is collected through a structured self-administered online questionnaire distributed by e-mail to undergraduate and graduate students. Findings -The study confirms positive correlation between awareness, convenience, compatibility, interest, adoption intention and respondents' age, education level, digital devices ownership, their general IT and e-books usage habits and their perceptions of mobile e-book reading Apps that enhance tourists' experiences as a potential added value of Croatian tourist offer. Originality/value -While the study is limited in its scope, it contributes to the growing literature on mobile Apps in tourism. Considering the lack of previous similar studies, it is intended to stimulate future research that could provide deeper understanding of the multiple contribution of mobile Apps, which could benefit Croatia as a tourist destination and all its stakeholders.

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Meta-analysis of clinical studies on the efficacy of flavonoids in viral and viral-bacterial diseases in children

Cited by 2 publications

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Acute respiratory infections in children: current trends in antiviral therapy

Acute respiratory infections in children: current trends in antiviral therapy

E-Book Reading Applications – Innovative Technology as a Response to Growing Consumer Preferences and Its Implications for Tourism

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