Meta-analysis of the effect of β-glucan intake on blood cholesterol and glucose levels

Tiwari, Uma; Cummins, Enda

doi:10.1016/j.nut.2010.11.006

Cited by 158 publications

(113 citation statements)

References 38 publications

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“…β-Glucan is the major structural polysaccharides accounting for about 85% of oat cell wall and is a soluble fibre, which, depending on molecular length, forms viscous gels in aqueous solutions. Tiwari and Cummins (159) performed a recent metanalysis on the ability of β-glucans to reduce blood cholesterol and glucose TC, total cholesterol; FOS, fructooligosaccharides; scFOS, short-chain FOS; OFS, oligofructose; GOS, galactooligosaccharides; B-GOS, Bi 2 muno GOS; Gluc, glucose; LPa, lipoprotein(a).…”

Section: Reducing Cvd Risk With Prebioticsmentioning

confidence: 99%

‘The way to a man's heart is through his gut microbiota’ – dietary pro- and prebiotics for the management of cardiovascular risk

2014

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The human gut microbiota has been identified as a possible novel CVD risk factor. This review aims to summarise recent insights connecting human gut microbiome activities with CVD and how such activities may be modulated by diet. Aberrant gut microbiota profiles have been associated with obesity, type 1 and type 2 diabetes and non-alcoholic fatty liver disease. Transfer of microbiota from obese animals induces metabolic disease and obesity in germ-free animals. Conversely, transfer of pathogen-free microbiota from lean healthy human donors to patients with metabolic disease can increase insulin sensitivity. Not only are aberrant microbiota profiles associated with metabolic disease, but the flux of metabolites derived from gut microbial metabolism of choline, phosphatidylcholine and l-carnitine has been shown to contribute directly to CVD pathology, providing one explanation for increased disease risk of eating too much red meat. Diet, especially high intake of fermentable fibres and plant polyphenols, appears to regulate microbial activities within the gut, supporting regulatory guidelines encouraging increased consumption of whole-plant foods (fruit, vegetables and whole-grain cereals), and providing the scientific rationale for the design of efficacious prebiotics. Similarly, recent human studies with carefully selected probiotic strains show that ingestion of viable microorganisms with the ability to hydrolyse bile salts can lower blood cholesterol, a recognised risk factor in CVD. Taken together such observations raise the intriguing possibility that gut microbiome modulation by whole-plant foods, probiotics and prebiotics may be at the base of healthy eating pyramids advised by regulatory agencies across the globe. In conclusion, dietary strategies which modulate the gut microbiota or their metabolic activities are emerging as efficacious tools for reducing CVD risk and indicate that indeed, the way to a healthy heart may be through a healthy gut microbiota.

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Section: Reducing Cvd Risk With Prebioticsmentioning

confidence: 99%

‘The way to a man's heart is through his gut microbiota’ – dietary pro- and prebiotics for the management of cardiovascular risk

2014

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“…Esta viscosidad hace que los β-glucanos retrasen el vaciamiento gástrico e interfieran con el contacto entre las enzimas pancreáticas y sus substratos en el lumen intestinal, frenando los procesos de digestión y absorción de los nutrientes. Esta propiedad podría explicar el efecto de los β-glucanos sobre la reducción de las concentraciones plasmáticas de colesterol y del índice glicémico (8,13). Los estudios del efecto de β-glucanos sobre la absorción de colesterol han reportado resultados divergentes.…”

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ß-glucanos: ¿qué tipos existen y cuáles son sus beneficios en la salud?

2014

Rev. chil. nutr.

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INTRODUCCIÓNLa importancia de la fibra dietética como parte de una dieta equilibrada para la salud del ser humano está ampliamente reconocida. Los β-glucanos son un tipo de fibra soluble para los cuales se han propuesto efectos sobre la glicemia, los niveles de insulinemia, el colesterol y la inmunidad. Cereales como la cebada y la avena son reconocidos como buenas fuentes de β-glucanos pero también se pueden encontrar en algas y hongos. Asimismo, sus propiedades parecen estar relacionadas con su peso molecular, estructura química y características reológicas, las cuales pueden variar según el origen del β-glucano (1).Debido a sus efectos potenciales sobre la salud, la industria de alimentos ha utilizado cada vez más los β-glucanos para el desarrollo de alimentos funcionales. Además, sus propiedades reológicas han estimulado su incorporación a distintas matrices alimentarias con el objetivo de mejorar la estabilidad, textura y vida útil del alimento, en remplazo de ciertos aditivos o agentes texturizantes artificiales (2).En los cereales, los β-glucanos se encuentran concentradas en las paredes celulares del endospermo, cuyo desarrollo es dependiente de las condiciones geoclimáticas; estas, por lo tanto, inciden en el contenido de β-glucano del cereal. Este es regulado por la enzima β-glucano endohidrolasa (1→3, 1→4), también conocida como licheninasa o 1→3, 1→4 β-glucanasa, cuya función es promover la degradación de la pared celular

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“…β-glucans) to the food matrices or the inclusion of foods rich in soluble fiber such as oats and barley (Hordeum vulgare L.). Most of the health benefits associated with high viscosity foods are due to β-glucans, which demonstrated some physiological effects such as the satiety and the moderation of the glycemic and insulinemic postprandial response [37,72,73]. To understand if the β-glucans benefits are dose-dependent, several studies were conducted to define the lowest dose which demonstrated the effect above mentioned.…”

Section: Most Promising Functional Foods To Increase Satiety Accordinmentioning

confidence: 99%

Functional Food to Regulate Satiety and Energy Intake in Human

Alviña¹,

Araya²

2016

TOASJ

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Nowadays obesity is affecting people from all socioeconomic levels in most of the countries worldwide. Appetite and satiety are complex processes which influence the energy regulation. As a solution to enable individuals to control their body weight, functional foods were developed in order to reduce the energy intake. However, the methodology to assess the satiating efficiency of functional foods, including monitoring through biomarkers, is very complex and needs to be standardized. The aim of the present work was to analyse the results published in the area of functional food and satiety to demonstrate the potential satiating role of these foods.

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Meta-analysis of the effect of β-glucan intake on blood cholesterol and glucose levels

Cited by 158 publications

References 38 publications

‘The way to a man's heart is through his gut microbiota’ – dietary pro- and prebiotics for the management of cardiovascular risk

‘The way to a man's heart is through his gut microbiota’ – dietary pro- and prebiotics for the management of cardiovascular risk

ß-glucanos: ¿qué tipos existen y cuáles son sus beneficios en la salud?

Functional Food to Regulate Satiety and Energy Intake in Human

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