Casson fluid model is the most accurate mathematical expression for investigating the dynamics of fluids with non-zero plastic dynamic viscosity like that of blood. Despite huge number of published articles on the transport phenomenon, there is no report on the increasing effects of the Coriolis force. This report presents the significance of increasing not only the Coriolis force and reducing plastic dynamic viscosity, but also the Prandtl number and buoyancy forces on the motion of non-Newtonian Casson fluid over the rotating non-uniform surface. The relevant body forces are derived and incorporated into the Navier-Stokes equations to obtain appropriate equations for the flow of Newtonian Casson fluid under the action of Coriolis force. The governing equations are non-dimensionalized using Blasius similarity variables to reduce the nonlinear partial differential equations to nonlinear ordinary differential equations. The resulting system of nonlinear ordinary differential equations is solved using the Runge-Kutta-Gills method with the Shooting technique, and the results depicted graphically. An increase in Coriolis force and non-Newtonian parameter decreases the velocity profile in the x-direction, causes a dual effect on the shear stress, increases the temperature profiles, and increases the velocity profile in the z-direction.