Metabolic Correlates of Health-Related Quality of Life in Patients With Type 2 Diabetes Mellitus

Rani, Monika; Kumar, Rohit; Krishan, Pawan

doi:10.1177/0897190018760622

Cited by 5 publications

(6 citation statements)

References 34 publications

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“…Lack of freedom to eat the food of choice was implicated as a cause for poor QOL in people living with diabetes from Karnataka, India [11]. The presence of MetS, central obesity has been linked with poorer QOL in people living with T2DM from Punjab India [13].…”

Section: Aementioning

confidence: 99%

Predictors of quality of life in people living with type-1 and type-2 diabetes: An Indian perspective study and systematic review

Dutta

Khandelwal²,

Jain³

et al. 2021

Clinical Diabetology

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background. this study evaluated predictors of good QOL in people with type-1 diabetes (t1DM) and type 2 diabetes (t2DM) using validated general health questionnaire [World Health Organization's (WHO)-QOL-Brief (BREF) questionnaire] and diabetes-specific questionnaire [Multidimensional Diabetes Questionnaire (MDQ)]. Methods. consecutive people > 18 years age, having t1DM or t2DM of > 6 months duration, without any severe co-morbid states or hospital admission in last 3 months, attending endocrinology-clinics of 3 different centers in Delhi, between August 2014 to september 2019, underwent QOL assessment. PubMed and Medline search for articles published to till November 2019 on QOL in diabetes was done for systematic review. result. Data from 2067 patients was analyzed. WHO-QOL-BREF aggregate score was significantly better in t2DM compared to t1DM (3.39 ± 0.46 vs 3.11 ± 0.63; P < 0.001). T1DM did significantly better than T2DM patients only with regards to physical health. t1DM patients' QOL scores were worse for psychological, social relationship, and environmental domains. Analysis based on quartiles of WHO-QOL-brEF aggregate score revealed people in Quartile-4 were significantly older, had the lowest hypoglycemia, nephropathy, retinopathy, neuropathy, cAD, and peripheral artery disease. Patients with the lowest QOL (Quartile-1) had the highest blood glucose and HbA 1c . step-wise linear regression revealed age, sex, diabetes type, duration, HbA 1c , hypoglycemia, nephropathy, neuropathy, and coronary artery disease to be independent predictors of QOL. Every percent increase in HbA 1c was associated with a 2.1% reduction in aggregate QOL score. Hypoglycemia, the presence of nephropathy, and neuropathy were associated with a 9.1%, 11.4%, and 7.8% reduction in QOL aggregate score. conclusion. Younger age, female sex, t1DM, disease duration, glycaemic control, hypoglycemia end-organ damage are important predictors of poor QOL in Indians. Insulin use and a number of medications have no impact on QOL. (clin Diabetol 2021; 10)

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Section: Aementioning

confidence: 99%

Predictors of quality of life in people living with type-1 and type-2 diabetes: An Indian perspective study and systematic review

Dutta

Khandelwal²,

Jain³

et al. 2021

Clinical Diabetology

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“…Studies conducted so far have reported that quality of life decreases with the presence of complications 25,26,28,29,30,31,32 . Quality of life in individuals with type 2 diabetes varies depending on complications, presence of other diseases, and the duration of the disease 33,34,35 . In our study, 70% of the individuals with diabetes had an additional chronic disease.…”

Section: Discussionmentioning

confidence: 99%

Relationship between family support and quality of life in individuals with diabetes

Aslan

Tekir²,

Yıldız

2021

Cukurova Medical Journal

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This study aimed to investigate the relationship between family support and quality of life in individuals with diabetes. Materials and Methods: The universe of the study consisted of individuals receiving treatment in the Endocrinology Clinic of Balıkesir State Hospital. On the other hand, the sample of the study was made up of 260 individuals with diabetes who met the inclusion criteria and volunteered to participate in the study. Data collection forms included a questionnaire form, Hensarling's Diabetes Family Support Scale, and the Diabetes-Specific Quality of Life Scale. Results: A statistically significant relationship was found between the family status score, which is the subdimension of the Quality of Life Scale, and the total score of Hensarling's Diabetes Family Support Scale and its subdimension scores. As the family status score increased, the total score of the Hensarling's Diabetes Family Support Scale increased as well. There was no statistically significant relationship between the scores of other subscales. Conclusion: As the score of the family status subscale of the Quality of Life Scale of the individuals with diabetes increased, the total score of the Family Support Scale and its subscales increased as well. Amaç: Bu çalışmada diyabetli bireylerde aile desteği ile yaşam kalitesi arasındaki ilişkinin incelenmesi amaçlanmıştır. Gereç ve Yöntem: Araştırmanın evrenini, Balıkesir Devlet Hastanesi Endokrinoloji Kliniği'nde tedavi gören bireyler; araştırmanın örneklemini ise araştırmaya dahil edilme kriterlerine uyan ve araştırmaya katılmaya gönüllü olan 260 diyabetli birey oluşturmuştur. Veri toplama formları olarak; Anket Formu, Hensarling'in Aile desteği ölçeği, Diyabete Özgü Yaşam Kalitesi Ölçeği kullanılmıştır. Bulgular: Yaşam Kalitesinin alt boyutu olan aile durumu puanı ile Hensarling'in Diyabet Aile Destek Ölçeği toplam puanı ve alt boyut puanlarıyla arasında istatistiksel olarak anlamlı ilişki vardır. Aile durumu puanı arttıkça Hensarling' in Diyabet Aile Destek Ölçeği toplam puanı da artmaktadır. Diğer alt boyut puanlar arasında istatistiksel olarak anlamlı ilişki bulunmamaktadır. Sonuç: Diyabetli bireylerin Yaşam Kalitesi alt boyut puanı olan aile durumu puanı arttıkça Aile Desteği Ölçeği toplam puanı ve alt boyut puanları artmaktadır.

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“…Of the 41 reviewed studies, only two assessed QoL among T2D patients with comorbidities[ 24 ] or metabolic syndrome. [ 56 ] A stroke had a high negative impact on the physical HRQoL. The presence of comorbidities affected the physical component summary (PCS) and the mental component summary (MCS) of the Short Form Health Survey-12.…”

Section: R Esultsmentioning

confidence: 99%

“…[ 24 ] Among T2D diabetes patients with metabolic syndrome, a greater significant decline is observed in PCS and MCS as compared to those without metabolic syndrome. [ 56 ]…”

Section: R Esultsmentioning

confidence: 99%

“…The WHOQOL-BREF (10 studies)[ 25 26 29 30 35 36 57 58 59 60 ] and SF 36 (eight studies)[ 15 23 31 32 41 45 47 56 ] are the most commonly used generic instruments among T2D subjects in India. One study used both generic and diabetes-specific tools for QoL assessment and found that both instruments are equally effective and reliable in the evaluation of QoL among diabetes patients.…”

Section: R Esultsmentioning

confidence: 99%

See 1 more Smart Citation

Quality of Life and Diabetes in India: A Scoping Review

Aarthy

Mikocka‐Walus

Pradeepa

et al. 2021

Indian Journal of Endocrinology and Metabolism

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In recent years, numerous studies have explored the quality of life (QoL) in those with diabetes mellitus. The aim of this scoping review was to explore the current state of knowledge on QoL and its various associated factors among people with diabetes in India. Three databases were searched (PubMed, Scopus, and Medline) and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. A total of 41 articles were included in the review. The included studies were largely conducted in the Southern states and mainly investigated individuals with type 2 diabetes. The World Health Organization Quality of Life (WHOQOL-BREF) and Short Form Health Survey (SF-36) were the instruments used most often. In general, the studies showed that people with diabetes had poorer QoL than those without diabetes, and women with diabetes reported poorer QoL than men, consistent with findings across the world. However, the studies had significant methodological flaws which limit the validity and generalizability of the findings. Therefore, there is an urgent need to conduct high-quality QoL studies which are representative of all states of India as well as different types of diabetes in India in order to address this gap in the evidence.

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Metabolic Correlates of Health-Related Quality of Life in Patients With Type 2 Diabetes Mellitus

Abstract: The study demonstrated that patients with T2DM with MetS have overall poor HRQOL as compared to patients with T2DM without MetS.

Cited by 5 publications

References 34 publications

Predictors of quality of life in people living with type-1 and type-2 diabetes: An Indian perspective study and systematic review

Predictors of quality of life in people living with type-1 and type-2 diabetes: An Indian perspective study and systematic review

Relationship between family support and quality of life in individuals with diabetes

Quality of Life and Diabetes in India: A Scoping Review

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