Metabolic Effects Of Zinc (Review)

Distribution of Zinc in Muscle, Adipose Tissue and Blood Serum of Rats Under Conditions of Zinc-Deficient, Iodine-Deficient, High-Carbohydrate and High-Fat Diets

“…Numerous scientifi c studies have proven the signifi cant role of trace elements in the development of these pathologies. Among them is the essential trace element zinc, which participates in complex cascades of biochemical reactions of the body, affects the incremental activity of secretory organs; it is a part of a number of enzymatic substances and transporter proteins, which allows us to assert its signifi cant importance in the functioning of multicomponent regulatory systems [1][2][3]. According to the literature, about 17% of the world's population has a reduced concentration of zinc in the body [3].…”

“…Among them is the essential trace element zinc, which participates in complex cascades of biochemical reactions of the body, affects the incremental activity of secretory organs; it is a part of a number of enzymatic substances and transporter proteins, which allows us to assert its signifi cant importance in the functioning of multicomponent regulatory systems [1][2][3]. According to the literature, about 17% of the world's population has a reduced concentration of zinc in the body [3]. The average daily requirement of this trace element for an adult is about 11 mg for men, 8-10 mg for women, and 12-15 mg for pregnant women, breastfeeding mothers, children and adolescents [3,4].…”

“…According to the literature, about 17% of the world's population has a reduced concentration of zinc in the body [3]. The average daily requirement of this trace element for an adult is about 11 mg for men, 8-10 mg for women, and 12-15 mg for pregnant women, breastfeeding mothers, children and adolescents [3,4]. Zinc enters the human body with food (it is abundant in whole grain cereals, meat products, pumpkin seeds, pine nuts) and is absorbed by gastrointestinal organs.…”

“…Metalothioneins maintain zinc homeostasis, protect cells from the harmful effects of excess cations of the trace element and highly toxic chemical elements, in particular, cadmium, mercury, arsenic. Metalothioneins have anti-oxidant properties, as they inactivate free radicals [2,3]. Due to the large number of transporter proteins, zinc is involved in the signalling function that regulates cell differentiation, proliferation and growth [3,5].…”

“…Metalothioneins have anti-oxidant properties, as they inactivate free radicals [2,3]. Due to the large number of transporter proteins, zinc is involved in the signalling function that regulates cell differentiation, proliferation and growth [3,5].…”