Metabolic Profiling of Nine Mentha Species and Prediction of Their Antioxidant Properties Using Chemometrics

Abstract

Mentha species are well recognized for their medicinal and aromatic properties. The comprehensive metabolite profiles of nine Mentha species have been determined. The extracts of these Mentha species were also screened for antioxidant and free radical scavenging activities. Forty-seven hydrophilic and seventeen lipophilic compounds were identified and quantified from the selected Mentha species. Also, eleven phenolic compounds, riboflavin and eight carotenoids were present, and their composition and content varied among the various Mentha species. The different Mentha species exhibited a range of antioxidant potencies. Horse mint especially exhibited the strongest antioxidant capacities (1,1-diphenyl-2-picryl-hydrazyl (DPPH), hydrogen peroxide, and reducing power assay) among the nine Mentha species. A difference between different samples from the same species was not observed by multivariate analysis. A high correlation between metabolites involved in closely linked biosynthetic pathways has been indicated. The projection to latent structure method, using the partial least squares (PLS) method, was applied to predict antioxidant capacities based on the metabolite profiles of Mentha leaves. According to the PLS analysis, several carotenoid contents, such as E-β-carotene, 9Z-β-carotene, 13Z-β-carotene and lutein, as well as phenolic compounds, showed a positive relationship in reducing the power of Mentha extracts. Horse mint is a good candidate because of its high antioxidant efficacy among the nine Mentha species included in the study.

Changes in the Content of Phenolic Compounds and Biological Activity in Traditional Mexican Herbal Infusions with Different Drying Methods

“…This would be a response to the high content of these Compounds in these drying methods. The polyphenols present in spices have positive effects on health, proving the effectiveness by in vitro tests of the elimination of free radicals (DPPH and ABTS) and the reduction of metal ions (FRAP) [30], in such a way that this could be an explanation of the antioxidant activities of spices. The biological activity of plants is shown to be useful for the treatment of various diseases, especially chronic non transmissible diseases such as diabetes.…”

Horsemint as a potential raw material for the food industry: survey on the chemistry of a less studied mint species

“…Rutin content was found to be in significant correlation with the FRAP activity of M. longifolia (Patonay et al 2017). Park et al (2019) also observed strong antioxidant activity to their rutin-dominated M. longifolia sample. Further studies are suggested to determine if higher concentrations of quercetin derivatives are really universal characteristics to this species as it was described in some references above.…”

“…(20,000-80,000 mg/kg dp). On the other hand, a recent work (Park et al 2019) gives unconventionally low RA concentration (18.68 lg/g dp. viz.…”

“…(Table 4.). The concentration ranges are variable, like in the case of rutin: 0.822 mg/100 g dp (Benedec et al 2013) or 11 66 mg/100 g dp (Park et al 2019). Flavonol-rich samples were reported from Serbia (Stanislavljević et al 2012), Hungary (Patonay et al 2017) and Korea (Park et al 2019).…”

“…The concentration ranges are variable, like in the case of rutin: 0.822 mg/100 g dp (Benedec et al 2013) or 11 66 mg/100 g dp (Park et al 2019). Flavonol-rich samples were reported from Serbia (Stanislavljević et al 2012), Hungary (Patonay et al 2017) and Korea (Park et al 2019). Interestingly, Stanislavljević et al (2012) reported astragalin to be the dominant flavonol constituent of a M. longifolia charge (61.36 mg/g extract calculated with yield: 7118 mg/kg dp).…”