Metabolic rate and genomic GC. What we can learn from teleost fish

Uliano, E.; Chaurasia, Ankita; Berná, Luisa; Agnisola, Claudio; D’Onofrio, Giuseppe

doi:10.1016/j.margen.2010.02.001

Cited by 13 publications

(36 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is however possible that other factors besides temperature affect the methylation level in fish living at great depths (Varriale and Bernardi, 2006). In this respect the direct correlation between GC composition and metabolic rate recently described in various teleost species living in different habitats is quite interesting (Uliano et al, 2010).…”

Section: Resultsmentioning

confidence: 97%

Genome size, GC percentage and 5mC level in the Indonesian coelacanth Latimeria menadoensis

et al. 2011

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 97%

Genome size, GC percentage and 5mC level in the Indonesian coelacanth Latimeria menadoensis

et al. 2011

View full text Add to dashboard Cite

“…It is worth to bring to mind that in a larger dataset of 34 teleostean species the correlation between MR and GCg was highly significant, p -value<2.5×10 −3 [24]. For each pair of species, the Δ MR values were computed and correlated with the corresponding Δ GCi and Δ bpi average values obtained before running RepeatMasker.…”

Section: Resultsmentioning

confidence: 99%

“…A comprehensive analysis on a large dataset of fish genomes showed that not only the routine metabolic rate (temperature-corrected by Boltzmann's factor) was affected by the living habitat of the species, but also the genomic GC content, both decreasing from polar to tropical environment [24]. A more detailed analysis showed that the variability of the GC content among fishes living in different habitat was not dictated by a dissimilar rate of the methylation-deamination process of the CpG doublets [25].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Length and GC Content Variability of Introns among Teleostean Genomes in the Light of the Metabolic Rate Hypothesis

et al. 2014

Self Cite

View full text Add to dashboard Cite

A comparative analysis of five teleostean genomes, namely zebrafish, medaka, three-spine stickleback, fugu and pufferfish was performed with the aim to highlight the nature of the forces driving both length and base composition of introns (i.e., bpi and GCi). An inter-genome approach using orthologous intronic sequences was carried out, analyzing independently both variables in pairwise comparisons. An average length shortening of introns was observed at increasing average GCi values. The result was not affected by masking transposable and repetitive elements harbored in the intronic sequences. The routine metabolic rate (mass specific temperature-corrected using the Boltzmann's factor) was measured for each species. A significant correlation held between average differences of metabolic rate, length and GC content, while environmental temperature of fish habitat was not correlated with bpi and GCi. Analyzing the concomitant effect of both variables, i.e., bpi and GCi, at increasing genomic GC content, a decrease of bpi and an increase of GCi was observed for the significant majority of the intronic sequences (from ∼40% to ∼90%, in each pairwise comparison). The opposite event, concomitant increase of bpi and decrease of GCi, was counter selected (from <1% to ∼10%, in each pairwise comparison). The results further support the hypothesis that the metabolic rate plays a key role in shaping genome architecture and evolution of vertebrate genomes.

show abstract

“…For fishes, interspecific studies of MR show mixed support for MCA [17,18,22,23,25,26], while studies at other levels of organization have revealed patterns consistent with MCA. The activities of enzymes associated with energy metabolism are typically higher in species from polar and temperate environments than in those from tropical environments [27,28], and mitochondrial volume density is relatively high in the muscles of Antarctic fishes [29,30].…”

Section: Introductionmentioning

confidence: 99%

Metabolic cold adaptation in fishes occurs at the level of whole animal, mitochondria and enzyme

2011

View full text Add to dashboard Cite

Metabolic cold adaptation (MCA), the hypothesis that species from cold climates have relatively higher metabolic rates than those from warm climates, was first proposed nearly 100 years ago and remains one of the most controversial hypotheses in physiological ecology. In the present study, we test the MCA hypothesis in fishes at the level of whole animal, mitochondria and enzyme. In support of the MCA hypothesis, we find that when normalized to a common temperature, species with ranges that extend to high latitude (cooler climates) have high aerobic enzyme (citrate synthase) activity, high rates of mitochondrial respiration and high standard metabolic rates. Metabolic compensation for the global temperature gradient is not complete however, so when measured at their habitat temperature species from high latitude have lower absolute rates of metabolism than species from low latitudes. Evolutionary adaptation and thermal plasticity are therefore insufficient to completely overcome the acute thermodynamic effects of temperature, at least in fishes.

show abstract

Metabolic rate and genomic GC. What we can learn from teleost fish

Cited by 13 publications

References 42 publications

Genome size, GC percentage and 5mC level in the Indonesian coelacanth Latimeria menadoensis

Genome size, GC percentage and 5mC level in the Indonesian coelacanth Latimeria menadoensis

Length and GC Content Variability of Introns among Teleostean Genomes in the Light of the Metabolic Rate Hypothesis

Metabolic cold adaptation in fishes occurs at the level of whole animal, mitochondria and enzyme

Contact Info

Product

Resources

About