Metabolic signatures altered by in vitro temperature stress in Ajuga bracteosa Wall. ex. Benth.

Rani, Rehana; Khan, Mubarak Ali; Kayani, Waqas Khan; Ullah, Sami; Naeem, Ijaz; Mirza, Bushra

doi:10.1007/s11738-017-2394-9

Cited by 29 publications

(8 citation statements)

References 22 publications

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“…The results were 12.38 ± 0.22 mg RE/g dw [23], which is in accordance with the current results (11.26 ± 0.58 and 14.05 ± 0.41 mg RE/g dw). A recent study performed by Rani et al (2017) revealed a TFC value of 9.3 mg QE/g dw for Ajuga bracteosa [26].…”

Section: Resultsmentioning

confidence: 99%

Comparative Phytochemical Profile, Antioxidant, Antimicrobial and In Vivo Anti-Inflammatory Activity of Different Extracts of Traditionally Used Romanian Ajuga genevensis L. and A. reptans L. (Lamiaceae)

et al. 2019

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Several Ajuga species are used in Romanian folk medicine for their antioxidant, antimicrobial and anti-inflammatory properties, to treat pain, fever or arthritis. Still, the active compounds responsible for these effects and their mechanism of action are scarcely known. This research was designed to investigate the phytochemical profile (e.g. iridoids, polyphenolic compounds, phytosterols), as well as the biological potential (antioxidant, antibacterial, antifungal, anti-inflammatory properties) of two selected Ajuga species collected from different regions of Romanian spontaneous flora. The main compounds identified in A. reptans aerial parts extracts were 8-O-acetylharpagide, isoquercitrin and β-sitosterol, whilst in A. genevensis were 8-O-acetylharpagide, luteolin and campesterol. The extracts were screened for their antioxidant potential using different methods (DPPH, TEAC, EPR) and the results showed a good activity, in accordance with the polyphenol content (18–26 mg GAE/g dw). The antifungal activity on the tested strains was good. The determination of few parameters linked with the inflammatory mechanism allowed the assessment of in vivo anti-inflammatory potential. Ajuga reptans and A. genevensis ethanol extracts had anti-inflammatory activity through lowering the oxidative stress, phagocytosis, PMN and total leukocytes. The best anti-oxidative and anti-inflammatory activity was observed for the Ajuga reptans 100 mg dw/mL extract when compared with diclofenac, thus the dose could be correlated with the pharmacological effect. These findings provide substantial evidence that both selected Ajuga species have the potential to be valued as sources of phytochemicals in effective anti-inflammatory herbal preparations.

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Section: Resultsmentioning

confidence: 99%

Comparative Phytochemical Profile, Antioxidant, Antimicrobial and In Vivo Anti-Inflammatory Activity of Different Extracts of Traditionally Used Romanian Ajuga genevensis L. and A. reptans L. (Lamiaceae)

et al. 2019

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“…Among different plant cell culture strategies, callus culture is a preferred strategy for the efficient and feasible production of healthy plant material with enhanced bioactive phytochemicals. Callus can also be used as a starting material for the in vitro regeneration of entire plantlets [20,21].…”

Section: Introductionmentioning

confidence: 99%

Interactive effects of zinc oxide nano particles and different light regimes on growth and silymarin biosynthesis in callus cultures of Silybum marianum L.

Shehzad

Khan

Ali

et al. 2021

Artificial Cells, Nanomedicine, and Biotechnology

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“…Among the various plant cell culture approaches, callus culture is the suitable method for feasible production of healthy plant material and bio active phytochemicals. Callus can be manipulated further for the in vitro regeneration of entire plants [10,11]. Till date, no previous research article is available in literature to show the effects of AgNPs on callus biomass formation and production of antioxidants in callus cultures of C. tuberculata.…”

Section: Introductionmentioning

confidence: 99%

Silver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata

Ali

Mohammad

Khan

et al. 2019

Artificial Cells, Nanomedicine, and Biotechnology

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130

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Metabolic signatures altered by in vitro temperature stress in Ajuga bracteosa Wall. ex. Benth.

Cited by 29 publications

References 22 publications

Comparative Phytochemical Profile, Antioxidant, Antimicrobial and In Vivo Anti-Inflammatory Activity of Different Extracts of Traditionally Used Romanian Ajuga genevensis L. and A. reptans L. (Lamiaceae)

Comparative Phytochemical Profile, Antioxidant, Antimicrobial and In Vivo Anti-Inflammatory Activity of Different Extracts of Traditionally Used Romanian Ajuga genevensis L. and A. reptans L. (Lamiaceae)

Interactive effects of zinc oxide nano particles and different light regimes on growth and silymarin biosynthesis in callus cultures of Silybum marianum L.

Silver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata

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