2019
DOI: 10.3748/wjg.v25.i43.6465
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Metabolic syndrome attenuates ulcerative colitis: Correlation with interleukin-10 and galectin-3 expression

Abstract: BACKGROUNDUlcerative colitis (UC) is a chronic disease characterized by inflammation of intestinal epithelium, primarily of the colon. An increasing prevalence of metabolic syndrome (MetS) in patients with UC has been documented recently. Still, there is no evidence that MetS alters the course of the UC.AIMTo test the influence of the MetS on the severity of UC and the local and systemic immune status.METHODSEighty nine patients with de novo histologically confirmed UC were divided in two groups, according to … Show more

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Cited by 27 publications
(32 citation statements)
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“…Fecal samples were prepared as previously reported ( 24 ). Feces were collected and stored −80°C until analysis.…”
Section: Methodsmentioning
confidence: 99%
“…Fecal samples were prepared as previously reported ( 24 ). Feces were collected and stored −80°C until analysis.…”
Section: Methodsmentioning
confidence: 99%
“…MetS affects the course of the UC by alleviating the clinical presentation and severity of the disease (Jovanovic et al 2019). Milder form of UC in patients with MetS was accompanied by higher level of Gal-3 and interleukin-10 and less pronounced lymphocytes infiltration in affected tissue (Jovanovic et al 2019). Still, MetS is complex disease that goes through multiple stages and it is not known how individual stages affect the course of the UC.…”
Section: Discussionmentioning
confidence: 99%
“…As described in our previous study, the blood and feces were collected from UC patients with MetS at 8:00 a.m. (Jovanovic et al 2019). Sera and liquid feces fraction were separated and stored at −80°C before use.…”
Section: Measurement Of Cytokines Levels In Serum and Fecesmentioning
confidence: 99%
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