2020
DOI: 10.3390/ijms21165617
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Metabolic Syndrome, Clusterin and Elafin in Patients with Psoriasis Vulgaris

Abstract: Background: Psoriasis is a pathological condition characterized by immune system dysfunction and inflammation. Patients with psoriasis are more likely to develop a wide range of disorders associated with inflammation. Serum levels of various substances and their combinations have been associated with the presence of the disease (psoriasis) and have shown the potential to reflect its activity. The aim of the present study is to contribute to the elucidation of pathophysiological links between psoriasis, its pro… Show more

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Cited by 16 publications
(11 citation statements)
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References 63 publications
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“…7 In recent decades, increasing evidence has shown that metabolic syndrome (MetS) is a main complication of psoriasis. 8,9 MetS is a cluster of comorbid conditions, including obesity, dyslipidemia, hypertension and glucose intolerance. 10 Its pathogenesis involves insulin resistance and altered adipocyte…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…7 In recent decades, increasing evidence has shown that metabolic syndrome (MetS) is a main complication of psoriasis. 8,9 MetS is a cluster of comorbid conditions, including obesity, dyslipidemia, hypertension and glucose intolerance. 10 Its pathogenesis involves insulin resistance and altered adipocyte…”
Section: Introductionmentioning
confidence: 99%
“…Psoriasis affects 2–3% of the general population 2 and is associated with significant morbidity when present along with other comorbidities such as obesity, 3 cardiovascular disease, 4 hyperuricemia, 5,6 and chronic obstructive pulmonary disease 7 . In recent decades, increasing evidence has shown that metabolic syndrome (MetS) is a main complication of psoriasis 8,9 …”
Section: Introductionmentioning
confidence: 99%
“…It is associated with multiple comorbidities (Boehncke and Schon, 2015 ). Studies have demonstrated that individuals with psoriasis are at an increased risk of metabolic disorders, such as dyslipidemia, diabetes mellitus, obesity, and non-alcoholic fatty liver disease (NAFLD) (Khalid et al, 2013 ; Candia et al, 2015 ; Lonnberg et al, 2016 ; Rutter et al, 2016 ; Rodriguez-Zuniga and Garcia-Perdomo, 2017 ; Takeshita et al, 2017 ; Gui et al, 2018 ; Holmannova et al, 2020 ). In particular, metabolic comorbidities induce a greater risk of severe vascular diseases in patients with psoriasis.…”
Section: Introductionmentioning
confidence: 99%
“…According to recent evidence, MetS has been recognized as an important comorbidity of psoriasis. 19 There is a prevalence of 32% for MetS among adult patients with psoriasis globally. 20 The prevalence is different between locations.…”
Section: Discussionmentioning
confidence: 99%