Metal ion release from titanium with active oxygen species generated by rat macrophagesin vitro

Mu, Ying; Kobayashi, Takeshi; Sumita, Masato; Yamamoto, Akiko; Hanawa, Takao

doi:10.1002/(sici)1097-4636(200002)49:2<238::aid-jbm12>3.0.co;2-j

Cited by 123 publications

(58 citation statements)

References 49 publications

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“…This is due, partly, to the stability and corrosion resistance that results from the native titanium dioxide film that protects the metal from further oxidation [28]. It is commonly accepted that titanium exhibits high stability and corrosion resistance in vitro [29,30], although there have been reports showing the accumulation of titanium in tissues adjacent to the implant [31,32] that signifies metal release and some degree of corrosion in vivo. Aziz-Kerrzo et al [33] investigated the corrosion resistance of Ti, Ti-6Al-4V, and Ti-45Ni in a buffered saline solution using electrochemical methods.…”

Section: Surface Structure and Propertiesmentioning

confidence: 99%

Surface modification of titanium, titanium alloys, and related materials for biomedical applications

Liu

Chu

Ding

2004

Materials Science and Engineering: R: Reports

3,079

1,477

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Titanium and titanium alloys are widely used in biomedical devices and components, especially as hard tissue replacements as well as in cardiac and cardiovascular applications, because of their desirable properties, such as relatively low modulus, good fatigue strength, formability, machinability, corrosion resistance, and biocompatibility. However, titanium and its alloys cannot meet all of the clinical requirements. Therefore, in order to improve the biological, chemical, and mechanical properties, surface modification is often performed. This article reviews the various surface modification technologies pertaining to titanium and titanium alloys including mechanical treatment, thermal spraying, sol-gel, chemical and electrochemical treatment, and ion implantation from the perspective of biomedical engineering. Recent work has shown that the wear resistance, corrosion resistance, and biological properties of titanium and titanium alloys can be improved selectively using the appropriate surface treatment techniques while the desirable bulk attributes of the materials are retained. The proper surface treatment expands the use of titanium and titanium alloys in the biomedical fields. Some of the recent applications are also discussed in this paper. #

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Section: Surface Structure and Propertiesmentioning

confidence: 99%

Surface modification of titanium, titanium alloys, and related materials for biomedical applications

Liu

Chu

Ding

2004

Materials Science and Engineering: R: Reports

3,079

1,477

View full text Add to dashboard Cite

show abstract

“…Some studies using a surface reaction model have suggested that a titanium-peroxide complex is formed due to interaction with hydrogen peroxide when titanium is implanted in the human body [7][8][9] . Furthermore, the titanium surface was oxidized and dissolved by peroxide produced by bacteria and leukocytes during inflammatory reactions [10][11][12][13][14] . Similarly, in vitro studies have reported a decrease in resistance to corrosion and signs of pitting corrosion in titanium in the presence of hydrogen peroxide 6,[15][16][17] .…”

Section: Introductionmentioning

confidence: 99%

Discoloration of titanium alloy in acidic saline solutions with peroxide

et al. 2013

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The objective of this study was to compare corrosion behavior in several titanium alloys with immersion in acidulated saline solutions containing hydrogen peroxide. Seven types of titanium alloy were immersed in saline solutions with varying levels of pH and hydrogen peroxide content, and resulting differences in color and release of metallic elements determined in each alloy. Some alloys were characterized using Auger electron spectroscopy. Ti-55Ni alloy showed a high level of dissolution and difference in color. With immersion in solution containing hydrogen peroxide at pH 4, the other alloys showed a marked difference in color but a low level of dissolution. The formation of a thick oxide film was observed in commercially pure titanium showing discoloration. The results suggest that discoloration in titanium alloys immersed in hydrogen peroxide-containing acidulated solutions is caused by an increase in the thickness of this oxide film, whereas discoloration of Ti-55Ni is caused by corrosion.

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“…This is due, partly, to the stability and corrosion resistance exhibited by titanium, which in turn is due to the spontaneous formation of a passive titanium dioxide "lm, typically a few nm thick, which protects the metal from further oxidation [1]. It is commonly accepted that titanium exhibits a high stability and a high corrosion resistance in vitro [2,3], although there are reports, which show the accumulation of titanium in tissues adjacent to the implant [4,5], signifying metal release and corrosion in vivo.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical studies on the stability and corrosion resistance of titanium-based implant materials

et al. 2001

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The corrosion susceptibility of Ti, Ti}6Al}4V and Ti}45Ni was studied in a bu!ered saline solution using anodic polarisation and electrochemical impedance measurements. Pitting potentials as low as#250 mV(SCE) were recorded for Ti}45Ni and once initiated pits continued to propagate at potentials as low as !150 mV(SCE). It was possible to increase the pitting potential of Ti}45Ni to values greater than #800 mV(SCE) using a H O surface treatment procedure; however, this surface modi"cation process had no bene"cial e!ect on the rate of pit repassivation. Impedance spectra, recorded under open-circuit conditions, were modelled using a dual oxide "lm model; a porous outer layer and an inner barrier oxide layer. The nature of this porous outer layer was found to depend on the nature of the electrode material and the presence of phosphate anions in the saline-bu!ered solution. The porous layers formed on Ti}45Ni and Ti}6Al}4V in the presence of phosphate anions had low resistances typically between 10 and 70 cm . Much higher porous layer resistances were recorded for Ti and also for Ti}45Ni and Ti}6Al}4V in the absence of the phosphate anions.

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Metal ion release from titanium with active oxygen species generated by rat macrophagesin vitro

Cited by 123 publications

References 49 publications

Surface modification of titanium, titanium alloys, and related materials for biomedical applications

Surface modification of titanium, titanium alloys, and related materials for biomedical applications

Discoloration of titanium alloy in acidic saline solutions with peroxide

Electrochemical studies on the stability and corrosion resistance of titanium-based implant materials

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