“…The coordination of diamond-like shapes MIL-100(Fe) particles produces small pore opening, in each cell unit 20 . Upon activation, the pore size can reach 29 Å and 24 Å for each large and small pore, respectively 14,21 . For comparison purposes, the synthesized MIL-100(Fe), from this study, was characterized using XRD, SEM, N 2 sorption, and TGA.Figure 2Illustrated crystal structure of MIL-100(Fe).…”
Sustainable development of drug delivery materials with good biocompatibility and controlled-release is a popular topic among researchers. In this research study, we demonstrated the potential of the metal-organic framework, that is MIL-100(Fe), as a drug delivery platform for isoniazid (INH). The MIL-100(Fe) was prepared by using the hydrofluoric acid-free hydrothermal method. Several physical measurements were conducted to characterize the MIL-100(Fe), including x-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen sorption, and thermal-gravimetric (TG). The synthesized MIL-100(Fe) has octahedron-shaped particles with superior properties, that is large surface area (1456.10 m2/g) and pore volume (1.25 cm3/g). The drug loading rate and capacity were determined by means of adsorption kinetic and isotherm. The studied INH@MIL-100(Fe) adsorption system kinetics follow the pseudo-first-order model, while the isotherm system follows the Langmuir model with the maximum adsorption capacity of 128.5 mg/g at 30 °C. MIL-100(Fe) shows adequate biocompatibility, also exhibits a reasonable and controlled drug release kinetics. The results obtained show that MIL-100 (Fe) can be a good choice of drug delivery platform among other available platforms.
“…The coordination of diamond-like shapes MIL-100(Fe) particles produces small pore opening, in each cell unit 20 . Upon activation, the pore size can reach 29 Å and 24 Å for each large and small pore, respectively 14,21 . For comparison purposes, the synthesized MIL-100(Fe), from this study, was characterized using XRD, SEM, N 2 sorption, and TGA.Figure 2Illustrated crystal structure of MIL-100(Fe).…”
Sustainable development of drug delivery materials with good biocompatibility and controlled-release is a popular topic among researchers. In this research study, we demonstrated the potential of the metal-organic framework, that is MIL-100(Fe), as a drug delivery platform for isoniazid (INH). The MIL-100(Fe) was prepared by using the hydrofluoric acid-free hydrothermal method. Several physical measurements were conducted to characterize the MIL-100(Fe), including x-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen sorption, and thermal-gravimetric (TG). The synthesized MIL-100(Fe) has octahedron-shaped particles with superior properties, that is large surface area (1456.10 m2/g) and pore volume (1.25 cm3/g). The drug loading rate and capacity were determined by means of adsorption kinetic and isotherm. The studied INH@MIL-100(Fe) adsorption system kinetics follow the pseudo-first-order model, while the isotherm system follows the Langmuir model with the maximum adsorption capacity of 128.5 mg/g at 30 °C. MIL-100(Fe) shows adequate biocompatibility, also exhibits a reasonable and controlled drug release kinetics. The results obtained show that MIL-100 (Fe) can be a good choice of drug delivery platform among other available platforms.
“…The chemical composition was studied by EDX yielding mapping results of each element that allows for knowing the homogeneity of the synthesized MOF. images provides data about the size and dispersion of those NPs [138]. These microscopies can be coupled with Energy Dispersive Spectroscopy (EDS) or Energy Dispersive X-ray Analysis (EDX or EDAX), which allows for determining the elemental quantitative and qualitative composition of MOF.…”
Section: Scanning Electron Microscopy (Sem) and Transmission Electronmentioning
confidence: 99%
“…Due to this inconvenience, other technologies are sought that allow for knowing the elementary analysis. Wavelength Dispersive X-ray Fluorescence (WDXRF), for instance, is a novel technique used for elemental analysis applications [137][138][139]. In WDXRF, all elements are excited, simultaneously yielding each one a characteristic radiation emission that is detected by a detector.…”
“…Scheme of the mechanism proposed for the Methyl orange (MO) photodegradation with several M@MIL-100 (M = Pt, Pd, Ag) under visible light (reproduced with permission from ref [138]…”
This review analyzes the preparation and characterization of metal organic frameworks (MOFs) and their application as photocatalysts for water purification. The study begins by highlighting the problem of water scarcity and the different solutions for purification, including photocatalysis with semiconductors, such as MOFs. It also describes the different methodologies that can be used for the synthesis of MOFs, paying attention to the purification and activation steps. The characterization of MOFs and the different approaches that can be followed to learn the photocatalytic processes are also detailed. Finally, the work reviews literature focused on the degradation of contaminants from water using MOF-based photocatalysts under light irradiation.
“…The reason behind these chemical interactions was the presence of partially positively-charged metal sites in the metal organic frameworks [30,31]. These positively charged metal sites can interact with negatively charged sites through electrostatic interactions, leading to the adsorption of phosphate ions [32]. Figure 9 shows the breakthrough curves for different influent flow rates of 1.0, 1.5 and 2.0 mL/min; the filler mass was 30 g, the influent concentration was 10 mg/L and the effluent phosphorus concentration was 0.5 mg when breakthrough occurred.…”
Section: Performance Of Phosphorus Removal Adsorbentsmentioning
In the current study, we investigated the kinetics and thermodynamics of phosphorus removal by zeolite/steel slag/fly ash/basalt (ZSFB) composite fiber. Kinetic analysis indicated that the adsorption of phosphorus is best fitted with the pseudo-second-order model. The maximum adsorption capacity of the fiber calculated by the Langmuir model was found to be 4.18 mg/g and the partition coefficient was 1.49 mg/g/µM. Thermodynamics results revealed that the Gibbs free energy ΔG0 of the composite fiber was negative, indicating that the adsorption is a spontaneous process; the standard enthalpy of reaction ΔH0 was positive, indicating that the adsorption is endothermic. Adsorption under different influencing factors and desorption experiments were conducted to investigate the phosphorus removal characteristics of ZSFB composite fiber. Dynamic adsorption and the phosphorus removal experiment were also conducted in a fixed-bed reactor to study factors affecting the time of breakthrough. Results indicate that the performance of ZSFB composite fiber was not relatively outstanding compared with nanomaterials and magnetic composites. However, its performance has already met the class A demands of “discharge standard of pollutants for municipal wastewater treatment plant” (GB18918-2002) which means it can be applied to remove phosphorus from real wastewater in a cost-effective way with low-priced raw materials.
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