Metal release from dental biomaterials

Brune, Dag

doi:10.1016/0142-9612(86)90097-9

Cited by 162 publications

(89 citation statements)

References 72 publications

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“…Despite the methodological limitations of this report (sample size, lack of statistical analysis), it has frequently been cited as proof of the problems associated with amalgam (Bang and Lain, 1986;Brune, 1986;Van Noortet al, 1987;Ziff, 1984;Ziff and Ziff, 1986 ). The only immunological parameter examined in this study was the percentage of T3 lymphocytes, which was shown to increase when restorations were removed, and to decrease when they were replaced.…”

Section: Resultsmentioning

confidence: 99%

Short-term changes in lymphocytes after placement of silver amalgam restorations in healthy subjects

et al. 1995

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Objectives. The purpose of this study was to evaluate the changes in lymphocyte subpopulations that have led to immune system alterations after amalgam restorations were placed. Methods. A controlled, quasi-experimental pretest-posttest design was used to investigate the immune effects of silver amalgam restorations in a sample of 60 individuals (30 experimental and 30 control subjects) aged 18 to 21 y. Two blood samples were obtained 15 d apart from each participant. In each experimental subject, two amalgam restorations were placed in posterior teeth immediately after the first blood sample was collected. The changes in lymphocyte subpopulations in the two groups were compared by multivariate analysis. Resu/ts.There was a greater change inT8 lymphocytes in experimental than in control subjects; increases in B, DR, NK, and CD45R lymphocytes were smaller in experimental than in control subjects; the changes in T3 and T4 lymphocytes did not differ significantly between the two groups. Significance. Despite the statistical significance of some differences between the two groups, the differences are not considered to be clinically relevant for the 2 wk time period after placement.

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Section: Resultsmentioning

confidence: 99%

Short-term changes in lymphocytes after placement of silver amalgam restorations in healthy subjects

et al. 1995

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“…4 Regulate the flame on a Blazer (Blazer, Farmingdale, New York) torch. 5 Fuse silver soldering on the stainless steel archwire. 6 Section and finish with abrasive rubber point.…”

Section: Cell Culturementioning

confidence: 99%

“…4 Recent studies have demonstrated the relationship between cells and metallic cations released from dental alloys. [5][6][7] The metal parts that remain in the oral cavity are subject to corrosion because this environment's physical properties, ie, the chemical and microbiological properties, stimulate the dissolution of metals. [8][9] Among the cations present in the alloys, gold and palladium (noble elements) may not be detected, whereas silver, copper, zinc, and gallium are always found.…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of Silver Solder Employed in Orthodontics

Freitas

Oshima

Menezes

et al. 2009

The Angle Orthodontist

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Objective: To test the null hypothesis that the silver soldering employed in orthodontics is not cytotoxic for fibroblasts. Materials and Methods: This in vitro study was performed using a culture of mice fibroblasts (lineage NIH/3T3), divided into four groups (n ϭ 10 each): control, negative control (stainless steel archwire), positive control (amalgam disks), and test group (silver soldering). After cell culture in complete Dulbecco modified eagle medium and achievement of confluence in 80%, the suspension was added to the plates of 24 wells containing the specimens and incubated in an oven at 37ЊC for 24 hours. The plates were analyzed on an inverted light microscope, photomicrographs were obtained, and the results were recorded as response rates based on modifications of the parameters of Stanford according to the size of the diffusion halo of the toxic substance and quantity of cell lysis. Results:The results revealed a maximum response rate for the silver soldering group, as well as severe inhibition of cell proliferation and growth, more round cells with mostly darkened and granular aspects, suggesting lysis with cell death. A similar response was seen in the positive control group. Conclusion: The hypothesis is rejected. The silver soldering used in orthodontics represents a highly cytotoxic material for the cells analyzed. (Angle Orthod. 2009;79:939-944.)

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“…However, at Eb (breakdown potential), the average value of nickel and chromium ions released were 60 to 68 and 50 to 53 µg/cm 2 respectively, after 1 hour and approximately 1440 and 1200 µg/cm 2 after 24 hours, which is almost three times greater than the dietary intake of nickel and chromium ions (normal 400 and 240 µg in about 24 hours). 12 The exaggerated values in this study could be attributed to the accelerated leaching which was done intentionally to determine the specific ion release. However, in clinical conditions, these values may be lower as they are not subjected to an accelerated leaching process.…”

Section: Accelerated Leaching Studymentioning

confidence: 99%

Evaluation of Corrosive Behavior of Four Nickel–chromium Alloys in Artificial Saliva by Cyclic Polarization Test:An in vitro Study

2017

World Journal of Dentistry

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Introduction: Dental casting alloys made of high noble alloys, noble alloys, and predominantly base metal alloys have been used in the fabrication of fixed and removable prosthetic dental appliances. Nickel-chromium (NiCr) alloy has been widely used in the fabrication of fixed and removable partial denture frameworks owing to its superior physical properties and lower cost, but their resistance to tarnish and corrosion is debatable.

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Metal release from dental biomaterials

Cited by 162 publications

References 72 publications

Short-term changes in lymphocytes after placement of silver amalgam restorations in healthy subjects

Short-term changes in lymphocytes after placement of silver amalgam restorations in healthy subjects

Cytotoxicity of Silver Solder Employed in Orthodontics

Evaluation of Corrosive Behavior of Four Nickel–chromium Alloys in Artificial Saliva by Cyclic Polarization Test:An in vitro Study

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