Metallothioneins and heat shock proteins 70 in marine mussels as sensors of environmental pollution in Northern Adriatic Sea

Lysosomal responses to heat-shock of seasonal temperature extremes in Cd-exposed mussels

“…This would explain the effective but promptly reversible response to heat-shock in Cd-exposed mussels and the return to lysosomal biomarker values characteristic of Cd-exposure alone. Likewise, seasonal acclimatisation to summer temperatures (enhanced MT and HSP70 pools; Hoffman and Somero, 1995;Micovic et al, 2009Micovic et al, 2009) might have contributed to protect against Cd-exposure in absence of thermal stress (T 0 ), at least at the very short term, which resulted in less responsive lysosomal biomarkers in summer than in winter.…”

“…Therefore, it seems that Cd-exposure was the dominant stress source but mussels were able also to respond to additional thermal stress. Indeed, the ability of mussels to up-regulate genes encoding heat-shock proteins does not seem to be compromised by Cd-exposure (Micovic et al, 2009). Besides, it is conceivable that Cdexposure might have facilitated the heat-shock response because Cd-response genes and HSP70 genes share a common regulatory mechanism (Lynes et al, 2007).…”

“…respond against thermal stress . Within this context, the interactive effects of pollutants and elevated temperatures in aquatic ectotherms have been increasingly investigated during the last years (Piano et al, 2004;Sokolova, 2004;Hallare et al, 2005;Cherkasov et al, 2006;Lannig et al, 2006;Ivanina et al, 2009;Micovic et al, 2009;Negri et al, 2013;Izagirre et al, 2014). However, though the relevance of extreme temperature events is gaining recognition, the majority of the studies on the interactions between thermal stress and pollution deal with the consequences of either gradual temperature elevation or acclimatisation to high temperatures at mid-and long-term.…”

Stress levels over time in the introduced ascidian Styela plicata: the effects of temperature and salinity variations on hsp70 gene expression

“…Besides temperature, other factors are also known to significantly stress marine organisms, including sharp salinity decreases (e.g., Kültz 1996;Deane and Woo 2004;Yang et al 2009), food constraints (e.g., Rossi et al 2006), hypoxia (e.g., Ma and Haddad 1997), ocean acidification (e.g., O'Donnell et al 2009), and the presence of pollutants (e.g., Müller et al 1995;Agell et al 2004;Azumi et al 2004;Micovic et al 2009;Su et al 2010;Bozinovic and Oleksiak 2011). Several studies have also documented the physiological response of organisms under a combination of multiple potential stressors (O'Donnell et al 2009;Lockwood et al 2010;Monari et al 2011).…”

Comparative sequence analysis of Hsp70 gene from Mytilus edulis desolationis and Aulacomya ater of the Kerguelen Islands

“…10,11 Their structural features are highly conserved among eukaryotes and prokaryotes, especially in the case of hsp70, a widely used biomarker to monitor the impact of environmental factors on various animal species, including mussels. [12][13][14][15][16] Unfortunately, while a considerable amount of data exists on blue mussel stress response genes, our knowledge on A. ater remains fragmentary. In the present work, we report a detailed comparative analysis of hsp70 stress response gene from Mytilus desolationis (M. desolationis) and Aulacomya ater (A. ater).…”