Metastatic abscessation and other potential complications following strangles

Whitlock, Fleur; Newton, J. R.; Waller, Andrew S.

doi:10.1111/eve.13012

Cited by 2 publications

(2 citation statements)

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“…equi infection is the most common cause of purpura haemorrhagica, but vaccination with M-proteincontaining vaccines, other bacteria, viruses, and neoplasia can similarly result in purpura complexes and vasculitis (Mallicote, 2015). Purpura haemorrhagica is caused by a type III hypersensitivity reaction, resulting in necrotising vasculitis secondary to immune-complex deposition (Whitlock et al, 2019). Its presentation can vary from innocuous to a potentially fatal complication (Boyle et al, 2018).…”

Section: Complications Ofstreptococcus Equi Infectionmentioning

confidence: 99%

The persistence of equine strangles

McLinden

Freeman

Daly

et al. 2022

Preprint

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Streptococcus equi subspecies equi (S. equi) is the causative organism of the upper respiratory disease of equids, strangles, characterised by pyrexia, lymphadenopathy, and mucopurulent nasal discharge. Strangles was first reported over 750 years ago and continues to be of significance in equine populations across the globe. This review discusses how S. equi has adapted, the clinical manifestation of strangles, and how clinicians and caregivers can tackle the disease in the future. S. equi evolved from the commensal, and occasionally opportunistic pathogen, Streptococcus equi subspecies zooepidemicus refining its capabilities as it became host restricted. The success of S. equi can be attributed to its ability to cause both acute and persistent infection, the latter occurring in about 10% of those infected. In this carrier state, S. equi persists in the guttural pouch without causing clinical signs, intermittently shedding into the environment, and encountering naïve animals. Insight into the S. equi genome and lifestyle has led to advances in diagnostic assays and the development of a safe and efficacious recombinant-fusion vaccine, giving clinicians and caregivers the tools to better combat this infection. Alongside rigorous biosecurity protocols and pragmatic control measures such as screening new arrivals for exposure and carrier status, these new technologies demonstrate that strangles can be an increasingly preventable infection.

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Section: Complications Ofstreptococcus Equi Infectionmentioning

confidence: 99%

The persistence of equine strangles

McLinden

Freeman

Daly

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Another potential complication is a tying-up like disease affecting muscles resulting in stiffness when walking (Kaese et al, 2005;Sponseller et al, 2005;Durward-Akhurst and Valberg, 2018). Abscesses can also form at other sites, known as metastatic disease, also termed 'bastard strangles' (Whitlock et al, 2018).…”

Section: Classical Signs Of Infection and Potential Complicationsmentioning

confidence: 99%