Metastatic cutaneous carcinosarcoma to the tongue

Tanaka, Norifumi; Hidaka, Shigekazu; Yamamura, Makoto; Ohyama, Hideki; Urade, Masahiro

doi:10.1016/j.ijom.2010.04.041

Cited by 9 publications

(10 citation statements)

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“…5,7 There are reports of very aggressive cutaneous carcinosarcomas, including cases of tumor recurrence and fatal metastatic spread. 8,9 With an estimated overall recurrence rate of 19%, a metastatic rate ranging from 7% to 29%, and a 5-year disease-free survival rate of 50%, several authors suggest that cutaneous carcinosarcoma must be recognized as an aggressive nonmelanoma skin cancer. 1,9,10 However, due to the small number of reported cases, tumor variation, and lack of long-term follow-up, the prognosis of cutaneous carcinosarcomas remains unclear.…”

Section: Discussionmentioning

confidence: 99%

Primary Cutaneous Carcinosarcoma of the Basal Cell Subtype Should Be Treated as a High-Risk Basal Cell Carcinoma

2015

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Section: Discussionmentioning

confidence: 99%

Primary Cutaneous Carcinosarcoma of the Basal Cell Subtype Should Be Treated as a High-Risk Basal Cell Carcinoma

2015

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“…Searching the literature revealed that, other than the cases we reported, tumors that showed oral/oropharyngeal metastases include uterine tumors and cervical cancer,8-10 carcinomas of the urinary bladder,11 leiomyosarcoma,12 alveolar soft part sarcoma,13 poorly differentiated carcinoma of the thyroid gland,14 medullary thyroid carcinoma,15 liposarcoma,16 and cutaneous carcinosarcoma 17. There are more published cases of jawbone metastases than of the oral soft tissues 2-4,18,19.…”

Section: Discussionmentioning

confidence: 87%

Metastatic Carcinomas to the Oral Cavity and Oropharynx

et al. 2012

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BackgroundMetastases to the oral/oropharynx are very rare and their diagnosis is challenging.MethodsWe reviewed pathologic data for malignant tumors of the oral/oropharynx that were diagnosed at the Asan Medical Center, Seoul, Korea from 1995 until 2010.ResultsTwenty-nine cases of oral/oropharyngeal metastases were retrieved, comprising 2.0% of 1,445 malignancies. The most common primary sites were the liver and lung, followed by the stomach, colon, breast, prostate, and kidney. The gingiva was the most common metastatic site, followed by the tonsil/pillar, mandible, tongue, tongue base, palate mucosa, mouth floor, and buccal mucosa. Intervals between detection of primary tumors and metastases were variable, from -1 month to 104 months. Ten patients with lung (7 cases), liver, stomach, and kidney carcinomas manifested with oral/oropharyngeal metastases as the first sign of systemic metastases. The majority of patients had died within one year of the onset of an oral/oropharyngeal metastasis, but exceptionally long-lived cases were also present. The survival periods of patients with lung cancers were longer than those of patients with non-pulmonary tumors.ConclusionsAn awareness of the incidence, common primary sites, metastatic subsites, and metastatic courses or patterns of oral/oropharyngeal metastases is helpful in the diagnosis of metastatic carcinomas.

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“…6) To date, 31 lingual metastases from lung cancer (9 adenocarcinomas, 8 mesotheliomas, 4 small cell carcinomas, 3 large cell carcinomas, 2 sarcomas, 2 fibrous histiocytomas, and 3 SCCs) have been reported in the literature. [4][5][6][7] Clinical presentation of malignant metastasis to the oral mucosa resembled a hyperplastic or reactive lesion, such as a pyogenic granuloma or submucosal mass. Lingual metastases typically located at the base or dorsolateral border of the tongue due to the rich vascular supply of lymphatics and blood.…”

Section: Discussionmentioning

confidence: 99%

“…In cases in which there is a single metastatic focus, surgical excision may be performed as a palliative measure for pain control, prevention of infection or bleeding, and maintenance of an acceptable level of oral function. 7) In one study in which the oral tumor was the only metastatic lesion, resection seemed to improve the prognosis of several patients, although the follow-up period was relatively short. 10) The prognosis of patients with lingual metastases is generally poor, since most already have widespread disease.…”

Section: Discussionmentioning

confidence: 99%