Metastatic prostatic carcinoma to breast or primary breast carcinoma?

Choudhury, Monisha; Wajsman, Zev; Derosas, J.; Beckley, S.; Papsidero, Lawrence D.; Pontes, J. Edson

doi:10.1016/0090-4295(82)90503-9

Cited by 18 publications

(6 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most authors found no association of prostatic cancer and breast cancer (Keller, 1967;Mabuchi et al, 1985;Schottenfeld et al, 1963). In contrast, in studies other than case-control studies, several investigators have mentioned a possible association between prostate cancer and male breast cancer (Choudhury et al, 1982;Marger et al, 1975;Schlappack et al, 1986;Sobin and Sherif, 1980). Sobin and Sherif (1980) found a worldwide correlation between the incidence of these 2 tumours, and this is confirmed in our data.…”

Section: Analytical Epidemiologysupporting

confidence: 85%

Review article: Epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors

Sasco

Lowenfels

Jong

1993

Intl Journal of Cancer

341

206

View full text Add to dashboard Cite

Male breast cancer is a rare tumour in all parts of the world. About 1% of all breast cancers occur in men, but the male/female ratio is higher among black than among white populations. This effect can be seen in US cancer registries and even more markedly in African data. A positive correlation exists on a population scale between male breast cancer and prostate cancer. Seven case-control studies of male breast cancer are available, and a pooled analysis was conducted of the most commonly suspected risk factors. Male breast cancer appears to be associated with marital status: Mantel-Haenszel exposure odds ratio (EOR) for never married = 1.6; 95% confidence limits (CL) = 1.1, 2.3, religion (EOR for being Jewish = 2.1; 95% CL = 1.4, 3.2), previous breast pathology (EOR for positive history of benign breast disease = 2.7; 95% CL = 1.7, 4.2), gynaecomastia (EOR for positive history = 6.2, 95% CL = 3.4, 11.4), previous testicular pathology (EOR for positive history = 2.2; 95% CL = 1.5, 3.3), previous liver diseases (EOR for positive history = 1.6; 95% CL = 1.0, 2.4) and family history of breast cancer (EOR for first-degree relative with breast cancer = 2.5; 95% CL = 1.7, 3.7). No association is found with smoking history. Other potential risk factors such as reproductive history, education, occupation, anthropometric variables, association with various diseases, and specific exposures such as drug use, were not systematically evaluated in all studies and provide sometimes contradictory results, possibly due to small numbers of exposed subjects. Overall, the analytical epidemiology of male breast cancer presents similarities with the epidemiology of female breast cancer, with a potential role of factors related to hormonal status, relative hyperoestrogeny in men being potentially linked to increased risk of disease. Genetics may also play a role, with high risk linked to a familial history of breast cancer, and with a major risk in patients with Klinefelter's syndrome.

show abstract

Section: Analytical Epidemiologysupporting

confidence: 85%

Review article: Epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors

Sasco

Lowenfels

Jong

1993

Intl Journal of Cancer

341

206

View full text Add to dashboard Cite

show abstract

“…In men, the prostate was the most common extramammary primary site of origin of metastasis to the breast. 12,14,15 The kidney has been rarely reported as the primary site of origin. Of 49 cases of metastatic tumors to the breast published in one series, 9 one case was from a renal-cell adenocarcinoma.…”

Section: Discussionmentioning

confidence: 99%

Fine-Needle Aspiration Cytology of Renal-Cell Adenocarcinoma Metastatic to the Breast: A Report of Three Cases

et al. 1999

View full text Add to dashboard Cite

Metastases to the breast from extramammary primary malignancies, including renal adenocarcinoma, are rare. Fine‐needle aspiration biopsy (FNA) is a useful, noninvasive, and rapid procedure to evaluate these mammary lesions. This study describes the cytomorphology of 3 cases of renal‐cell adenocarcinoma metastatic to the breast. All patients had a prior history of renal‐cell adenocarcinoma treated with radical nephrectomy, and they presented with a solitary mammary mass. The cytologic findings showed irregular clusters and dispersed single cells with eccentric nuclei and abundant, vacuolated cytoplasm in a hemorrhagic background. The nuclei were round to oval, with fine granular chromatin and a single, prominent nucleolus. All aspirates were interpreted initially and correctly as consistent with metastatic renal‐cell adenocarcinoma. In summary, a cytologic diagnosis of renal‐cell adenocarcinoma metastatic to the breast can be made by correlating clinical and cytologic findings. The distinction between metastatic extramammary malignancies to the breast and primary mammary carcinoma is critical to avoid unnecessary surgery and to ensure appropriate chemotherapy or radiation therapy. Diagn. Cytopathol. 21:324–327, 1999. © 1999 Wiley‐Liss, Inc.

show abstract

“…Both markers can be demonstrated in paraffin-embedded histological sec tions of prostatic carcinoma as well as its metastasis. These new methods have made possible the proper diag nosis of primary [4] and metastatic breast carcinomas [12,13] in current case reports.…”

Section: Histological and Histochemical Findingsmentioning

confidence: 99%

“…Since the first description by Abramson and Warshawsky [1] in 1948, more than 15 cases of primary breast cancer have been reported in prostatic cancer patients treated with estrogens [2][3][4]. Most authors insist that there is a causal relationship between estrogen and male breast cancer.…”

Section: Introductionmentioning

confidence: 99%

Breast Metastases of Prostatic Carcinoma: Immunohistochemical Case Study

Fukutani

Kawabe²,

Matsuki³

et al. 1987

Urol Int

View full text Add to dashboard Cite

A breast mass developed in a patient receiving estrogen therapy for prostatic cancer. The prostate tumor was adenocarcinoma of small acinar type, whereas that of the breast was infiltrating medullary adenocarcinoma. Histological features of the two tumors differed and double cancer was suspected by conventional pathological study. However, immunohistochemical staining with prostatic specific antigen and prostatic acid phosphatase was positive in each tumor. These results indicate the breast tumor to be a metastasis from the prostatic cancer.

show abstract

Metastatic prostatic carcinoma to breast or primary breast carcinoma?

Cited by 18 publications

References 24 publications

Review article: Epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors

Review article: Epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors

Fine-Needle Aspiration Cytology of Renal-Cell Adenocarcinoma Metastatic to the Breast: A Report of Three Cases

Breast Metastases of Prostatic Carcinoma: Immunohistochemical Case Study

Contact Info

Product

Resources

About