Methicillin-resistant staphylococci amongst veterinary personnel, personnel-owned pets, patients and the hospital environment of two small animal veterinary hospitals

Worthing, Kate A.; Brown, James; Gerber, L.J.; Trott, Darren J.; Abraham, Sam; Norris, Jacqueline M.

doi:10.1016/j.vetmic.2018.07.021

Cited by 45 publications

(53 citation statements)

References 47 publications

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“…The detection rate of S. aureus in pets (17.1%) was higher than in previous studies from China [9,31], Zambia [32], Canada [33], and Australia [34], but lower than in the previous study from Greece [35]. The frequency of MRSA in veterinarians (9.8%) was higher in our study than in the previous study from China [9], but lower than in previous studies from Australia [11]. Regarding environmental surfaces, the studies performed in veterinary hospitals [11] and households [10] showed rates of 0% and 46% in MRSA isolates, respectively.…”

Section: Discussioncontrasting

confidence: 83%

“…The frequency of MRSA in veterinarians (9.8%) was higher in our study than in the previous study from China [9], but lower than in previous studies from Australia [11]. Regarding environmental surfaces, the studies performed in veterinary hospitals [11] and households [10] showed rates of 0% and 46% in MRSA isolates, respectively. The airborne dust and unsterilized medical device also constituted the risk of spreading S. aureus [36,37].…”

Section: Discussioncontrasting

confidence: 78%

“…In addition, veterinarians and pets were found carrying MRSA. The higher detection rate of S. aureus in veterinarians (31.7%) than that of S. aureus in other sources supports the notion that S. aureus is generally more host-adapted to humans [11]. It is worth noting that S. aureus carriage rate in nasal swabs of male veterinarians reached 63.6% and was significantly different to the female veterinarians (0%, p < 0.05).…”

Section: Discussionsupporting

confidence: 56%

“…Alarmingly, numerous cases have been reported that humans may be infected with pet-associated S. aureus [7,8], and pets such as dogs and cats can serve as the reservoir of S. aureus [9,10]. Moreover, there have been increasing reports of S. aureus in companion animals, environmental surfaces, and humans from veterinary hospitals or households in the past few years [7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

“…The World Health Organization (WHO) has identified antibiotic resistance as one of the biggest challenges to global health and classified S. aureus as a high priority superbug for which research and development of novel antibiotics are needed urgently [17,18]. We should pay attention to the phenomenon that MRSA was constantly detected in companion animals and these strains generally show multidrug-resistance, significantly limiting the treatment options [9][10][11][12]19]. This multidrug resistance could be the result of careless antibiotics usage leading to wide resistance spectrum of MRSA isolated from companion animals [20].…”

Section: Introductionmentioning

confidence: 99%

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Biofilm Production Ability, Virulence and Antimicrobial Resistance Genes in Staphylococcus aureus from Various Veterinary Hospitals

et al. 2020

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Staphylococcus aureus (S. aureus) is one of the most clinically important zoonotic pathogens, but an understanding of the prevalence, biofilm formulation ability, virulence, and antimicrobial resistance genes of S. aureus from veterinary hospitals is lacking. By characterizing S. aureus in different origins of veterinary hospitals in Guangzhou, China, in 2019, we identified with the presence of S. aureus in pets (17.1%), veterinarians (31.7%), airborne dust (19.1%), environmental surfaces (4.3%), and medical device surfaces (10.8%). Multilocus sequence typing (MLST) and Staphylococcus protein A (spa) typing analyses demonstrated methicillin-sensitive S. aureus (MSSA) ST398-t571, MSSA ST188-t189, and methicillin-resistant S. aureus (MRSA) ST59-t437 were the most prevalent lineage. S. aureus with similar pulsed-field gel electrophoresis (PFGE) types distributed widely in different kinds of samples. The crystal violet straining assays revealed 100% (3/3) of MRSA ST59 and 81.8% (9/11) of MSSA ST188 showed strong biofilm formulation ability, whereas other STs (ST1, ST5, ST7, ST15, ST88, ST398, ST3154 and ST5353) showed weak biofilm production ability. Polymerase chain reaction (PCR) confirmed the most prevalent leucocidin, staphylococcal enterotoxins, ica operon, and adhesion genes were lukD-lukE (49.0%), sec-sel (15.7%), icaA-icaB-icaC-icaR (100.0%), and fnbB-cidA-fib-ebps-eno (100.0%), respectively. Our study showed that the isolates with strong biofilm production ability had a higher prevalence in clfA, clfB, fnbA and sdrC genes compared to the isolates with weak biofilm production ability. Furthermore, 2 ST1-MRSA isolates with tst gene and 1 ST88-MSSA isolate with lukS/F-PV gene were detected. In conclusion, the clonal dissemination of S. aureus of different origins in veterinary hospitals may have occurred; the biofilm production capacity of S. aureus is strongly correlated with ST types; some adhesion genes such as clfA, clfB, fnbA, and sdrC may pose an influence on biofilm production ability and the emergence of lukS/F-PV and tst genes in S. aureus from veterinary hospitals should raise our vigilance.

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Section: Discussioncontrasting

confidence: 83%

Section: Discussioncontrasting

confidence: 78%

Section: Discussionsupporting

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Biofilm Production Ability, Virulence and Antimicrobial Resistance Genes in Staphylococcus aureus from Various Veterinary Hospitals

et al. 2020

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Hospital Team Considerations

Nicholas¹,

Ackerman²,

Ballantyne

et al. 2021

Pet‐Specific Care for the Veterinary Team

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Dog‐assisted therapy in the dental clinic: Part A—Hazards and assessment of potential risks to the health and safety of humans

Gussgard

Weese

Hensten

et al. 2019

Clinical & Exp Dental Res

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BackgroundDog‐assisted therapy in the dental clinic may be an attractive alternative to sedation for anxious patients. Including a dental therapy dog in a clinical setting introduces new hazards and potential risks to health and safety for both humans and animal.ObjectivesThe study aims to describe potential hazards associated with risks to humans by having a therapy dog present in the dental clinic and to provide guidance on best practices to minimise and control risks for the patients, the dentist, and the dental clinic staff.Materials and MethodsLiterature searches in Medline, http://Clinicaltrials.gov, and Google Scholar for qualitative and quantitative assessments of hazards and risks associated with the use of therapy dogs in health care settings, in combination with a review of the reference list of the included studies. Identified hazards and risks were analysed with respect for the health and welfare of humans in a dental clinic setting that involves the presence of a therapy dog.ResultsPotential risks to health and safety for humans in dental clinics that offer dog‐assisted therapy can be categorised within four general categories of hazards: the dog as a source of zoonotic pathogens and human diseases, exposure to canine allergens, adverse animal behaviour, and dangers associated with high activity in a congested dental clinic operatory. Risks to humans are reduced by maintaining awareness amongst the dental clinic staff and the dog handler of all potential hazards in the dental clinic, and on how to reduce these hazards as well as adverse events that may scare the dental therapy dog.ConclusionsRisks to the health and safety of humans in the presence of therapy dog in the clinics are present but are low if the dental clinical staff and dog handlers comply with best practices.

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Methicillin-resistant staphylococci amongst veterinary personnel, personnel-owned pets, patients and the hospital environment of two small animal veterinary hospitals

Cited by 45 publications

References 47 publications

Biofilm Production Ability, Virulence and Antimicrobial Resistance Genes in Staphylococcus aureus from Various Veterinary Hospitals

Biofilm Production Ability, Virulence and Antimicrobial Resistance Genes in Staphylococcus aureus from Various Veterinary Hospitals

Hospital Team Considerations

Dog‐assisted therapy in the dental clinic: Part A—Hazards and assessment of potential risks to the health and safety of humans

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