Food supply is the most important component of the life support system and indicator of the population quality of life [1, 2]. In the scientific work, the assessment of the food supply level of the region was carried out, using the example of the Saratov region. The authors have identified the dynamics of indicators characterizing the food security of the region: acreage, livestock and poultry population, cost of agricultural products produced, cost of importing food and agricultural raw materials. The production dynamics of certain types of products, their production and personal consumption, as well as losses by volume are considered. With the help of these indicators, the level of self-sufficiency of the Saratov region with food resources of its own production is determined. The dynamics of the staple food consumption and the diet compliance with the recommended norms in kilograms per person per year are considered. The consumption by residents of the Saratov region of such types of food as potato, meat and meat products, vegetables, milk and dairy products does not comply with scientifically established medical standards, which causes a high share of imported products in actual food consumption and threatens the food security of the region.