Intelligence analysis of tabular datasets in the field of biomedical engineering is a complex task. This is explained both by the multidimensional datasets and the complex relationships between the components of the set, and by the high price of the error in the prediction. The task becomes more difficult in the case of limited data for training, which often occurs in this field. This is due to the enormous time, material, or human resources required to collect enough data to implement training procedures with classical machine learning tools. This paper presents a new approach to solving this task. The author has developed a new ensemble method for the regression model parameters adjustments (direct approach) with the possibility of cyclically increasing the accuracy of intellectual analysis of short datasets. The basis of the method is the use of the rational fraction and two machine learning algorithms for its parametric identification. Modeling of the method's efficiency on a real-world short set of data from the field of biomedical engineering demonstrated the high accuracy of the developed method's operation. In particular, the prediction accuracy of the General Regression Neural Network was increased by more than 14% (based on the coefficient of determination. That is why the developed method can be used to solve various applied biomedical engineering tasks in the case of the need to analyze small amounts of data