Some splines can be defined as solutions of differential multi-point boundary value problems (DMBVP). In the numerical treatment of DM-BVP, the differential operator is discretized by finite differences. We consider one dimensional discrete hyperbolic tension spline introduced in [2], and the associated specially structured pentadiagonal linear system.Error in direct methods for the solution of this linear system depends on condition numbers of corresponding matrices. If the chosen mesh is uniform, the system matrix is symmetric and positive definite, and it is easy to compute both, lower and upper bound, for its condition. In the more interesting non-uniform case, matrix is not symmetric, but in some circumstances we can nevertheless find an upper bound on its condition number.