2014
DOI: 10.1016/j.dental.2014.04.010
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Methods to evaluate and strategies to improve the biocompatibility of dental materials and operative techniques

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Cited by 112 publications
(114 citation statements)
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“…The number of samples for each group was determined according to previous studies that evaluated the effects of similar dental materials on dental pulp cells (5,11). After 24 h, 100 µL of the obtained extract (DMEM + components released from the cements) were collected and applied to the MDPC-23 cells in culture.…”
Section: Methodsmentioning
confidence: 99%
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“…The number of samples for each group was determined according to previous studies that evaluated the effects of similar dental materials on dental pulp cells (5,11). After 24 h, 100 µL of the obtained extract (DMEM + components released from the cements) were collected and applied to the MDPC-23 cells in culture.…”
Section: Methodsmentioning
confidence: 99%
“…After 60 days of direct application on the pulp tissue of human teeth, components arising from MTA with Bi 2 O 3 , were visualized in contact with the cytoplasm of endothelial cells and within blood vessels (11). Relevant and at the same time disconcerting scientific data such as these justify the development and constant improvement of new capping agents that must present adequate biological compatibility and bioactivity (12).…”
Section: Introductionmentioning
confidence: 99%
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“…Besides the high-quality dentin bond that is the goal of current adhesive dentistry, a concern regarding these dental materials is related to their biocompatibility with the pulp-dentin complex, especially when they are applied to deep dentin (5). The capability of residual monomers to elicit toxic reactions in pulp tissue is directly related to dentin permeability and humidity.…”
Section: Properties Of Universal Adhesive Systemsmentioning
confidence: 99%
“…Nevertheless, dentin etching increases permeability and hydraulic conductance at the pulpal wall upon removal of the smear layer and the opening of dentinal tubules (4). This high humidity interferes with the polymerization of adhesive systems, enhancing the local presence of toxic unreacted free monomers (2), which are capable of diffusing through dentin to cause pulp tissue damage (5).…”
Section: Introductionmentioning
confidence: 99%