Methylene Blue and Rose Bengal Photoinactivation of RNA Bacteriophages: Comparative Studies of 8-Oxoguanine Formation in Isolated RNA

Analytics of oxidative stress markers in the early diagnosis of oxygen DNA damage

“…[20][21][22][23][24] As with the hydroxyl radical, the mechanism for this attack is explained by two equally plausible theories. In both cases, the creation of 8-oxoguanine proceeds to form an intermediate product:…”

The Risk Evaluation of Tungsten Oxide Nanoparticles in Cultured Rat Liver Cells for Its Safe Applications in Nanotechnology

“…DNA was digested by incubation with DNAase I, endonuclease, and alkaline phosphatase (Schneider et al 1993). The amount of 8-OH-dG was measured by highperformance liquid chromatography (HPLC) with electrochemical detection as described previously .…”

Photodynamic treatment of adenoviral vectors with visible light: an easy and convenient method for viral inactivation

“…5,22,23 It is generally accepted that MB strongly associates with DNA and upon illumination, induces the formation of 8-hydroxyguanine (8-OHG). [24][25][26] Singlestranded nicks were observed as result of this 8-OHG formation. 24 The data presented here strongly indicate a preference of MB for DNA, as it was the only sensitizer tested that completely impaired the functional integrity of the viral DNA after a 5-min exposure (Figure 2).…”

“…[24][25][26] Singlestranded nicks were observed as result of this 8-OHG formation. 24 The data presented here strongly indicate a preference of MB for DNA, as it was the only sensitizer tested that completely impaired the functional integrity of the viral DNA after a 5-min exposure (Figure 2). Upon extended illumination (15 min), Southern analysis revealed DNA fragmentation.…”