Methylene chloride fraction of the leaves of Thuja orientalis inhibits in vitro inflammatory biomarkers by blocking NF-κB and p38 MAPK signaling and protects mice from lethal endotoxemia

Amelioration of an LPS-induced inflammatory response using a methanolic extract of Lagerstroemia ovalifolia to suppress the activation of NF-κB in RAW264.7 macrophages

“…The MAPKs are a group of signaling molecules that also appear to play critical roles in inflammatory processes (32). Evidence suggests that the activation of MAPKs is important in the regulation of NO production, through activation of NF-κB (33).…”

The anti-inflammatory activities of an extract and compounds isolated from Platycladus orientalis (Linnaeus) Franco in vitro and ex vivo

“…The traditional use of the plant as anti-inflammatory agents has been supported by several studies, which indicated that the extract or fractions of the plant possessed anti-inflammatory activity in animal models (Kim et al, 2011;Liang et al, 2003Liang et al, , 2004 or cell-based assays (Lee et al, 2010;Liang et al, 2001). The possible mechanism of the chemical constituents from the plant was elucidated to be related with inhibiting expression of adhesion molecules (Lee et al, 1999) and inducible nitric oxide synthase (iNOS) (Choi et al, 2008).…”

Antibacterial Effects of Extracts of Thuja Orientalis cv Aurea Nana Cones against Food-spoilage and Food-borne Pathogens

“…T. orientalis cv Aurea Nana is a dwarf plant with yellow-green leaves that compactly branch, which widely used as an ornamental plant in South Korea. It has been reported that the leaves of T. orientalis were used in the treatment of various inflammatory diseases (Kim et al, 2010). In Chinese herbal medicine, the leaves have been used for treatments of gout, rheumatism, diarrhea and chronic tracheitis (Zhu et al, 2004).…”