Entropy generation of fully developed steady, viscous, incompressible couple stress fluid in a vertical micro-porous-channel in the presence of horizontal magnetic field is analysed in this work. The governing equations for the flow are derived, and nondimensionalised and the resulting nonlinear ordinary differential equations are solved via a rapidly convergent technique developed by Zhou. The solution of the velocity and temperature profiles are utilised to obtain the flow irreversibility and Bejan number. The effects of couple stresses, fluid wall interaction parameter (FSIP), effective temperature ratio (ETR), rarefaction and magnetic parameter on the velocity profile, temperature profile, entropy generation and Bejan number are presented and discussed graphically.