The present study investigates the effect of thermal slip on an immiscible flow of micropolar and viscous fluids in a vertical channel. The left boundary is subjected to thermal slip with appropriate boundary and interface conditions, resulting in a linked system of nonlinear partial differential equations. The ND Solve technique in Mathematica software is used to implement the Runge-Kutta method of the sixth order. The velocity, temperature, and concentration equations are then calculated. The mass, heat, and velocity transmission rates at the boundaries were recorded for all the variations in the governing parameters. In addition, the impact of relevant parameters on various physical properties of micropolar and viscous fluids is analyzed through graphical means. The results are then discussed in detail. Thermal slip, Grashof number, molecular number, magnetic parameter, and Reynolds number are crucial factors that significantly affect heat and mass transfer in fluid flow. The effect of the increased thermal slip is noted to result in a decrease in both the velocity profile and temperature. It was also observed that higher values of Grashof and molecular Grashof numbers led to increased velocity and angular velocity.