Micellization and Adsorption of Fluorinated Amphiphiles: Questioning the 1 CF2≈1.5 CH2 Rule

Sadtler, Véronique; Giulieri, Françoise; Krafft, Marie Pierre; Riess, Jean G.

doi:10.1002/(sici)1521-3765(19981002)4:10<1952::aid-chem1952>3.0.co;2-v

Cited by 65 publications

(57 citation statements)

References 11 publications

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“…PFOS has a reduced charge density on the head-group and a more rigid hydrophobic tail in comparison to SDS. 56,57 The normalised UV/Vis absorption and PL spectra of the polythiophenes mixed with a 1 : 1 charge ratio of PFOS and, for comparison, SDS, are shown in The UV/Vis absorption spectra for P3HTPMe 3 (PFOS) 1 and P3HT-b-P3HTPMe 3 (PFOS) 1 are characterised by a single broad absorption band centred at 447 and 523 nm, respectively ( Fig. 3a and b), similar to the spectra for the pure CPEs.…”

Section: Optical Characterisationmentioning

confidence: 68%

A self-assembly toolbox for thiophene-based conjugated polyelectrolytes: surfactants, solvent and copolymerisation

et al. 2017

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Targeted control of the aggregation, morphology and optical properties of conjugated polymers is critical for the development of high performance optoelectronic devices. Here, self-assembly approaches are used to strategically manipulate the order, conformation and spatial distribution of conjugated polymers in solution and subsequently prepared thin films. The supramolecular complex organisation of phosphonium-functionalised homo- (P3HTPMe3) and diblock (P3HT-b-P3HTPMe3) ionic conjugated polythiophenes upon solvent-mediation and co-assembly with oppositely charged surfactants is investigated. UV/Vis absorption and photoluminescence spectroscopies, small-angle neutron scattering (SANS), cryo-transmission electron microscopy (cryo-TEM) and atomic force microscopy (AFM) are used to probe the organisation and photophysical response of the aggregates formed. Subtle differences in the surfactant mole fraction and structure, as well as the solvent polarity, yield differences in the nature of the resultant homopolyelectrolyte-surfactant complexes. In contrast, only moderate structural transformations are observed for the amphiphilic diblock copolyelectrolyte, emphasising the structure "anchoring" effect of a neutral polymer block when amphiphilic copolymers are dissolved in polar solvents. These results highlight the versatility of self-assembly to access a range of nanomorphologies, which could be crucial for the design of the next generation of organic optoelectronic devices.

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Section: Optical Characterisationmentioning

confidence: 68%

A self-assembly toolbox for thiophene-based conjugated polyelectrolytes: surfactants, solvent and copolymerisation

et al. 2017

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“…The physical chemistry of aqueous solutions of HFS forms a fascinating new field. Micellar properties, for instance, reflect the fact that the contributions of each section of the tail to the free enthalpy of transfer between water and the micellar core do not add linearly, as they do for fully hydrogenated or fluorinated surfactants [51,52]. The CMC of HFS is, indeed, higher than additivity would lead one to expect [35,53].…”

Section: Discussionmentioning

confidence: 99%

Hemifluorinated surfactants: a non‐dissociating environment for handling membrane proteins in aqueous solutions?

et al. 2004

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The instability of membrane proteins in detergent solution can generally be traced to the dissociating character of detergents and often correlates with delipidation. We examine here the possibility of substituting detergents, after membrane proteins have been solubilized, with non-detergent surfactants whose hydrophobic moiety contains a per£uorinated region that makes it lipophobic. In order to improve its a⁄nity for the protein surface, the £uorinated chain is terminated by an ethyl group. Test proteins included bacteriorhodopsin, the cytochrome b 6 f complex, and the transmembrane region of the bacterial outer membrane protein OmpA. All three proteins were puri¢ed using classical detergents and transferred into solutions of C 2 -H 5 C 6 F 12 C 2 H 4 -S-poly-Tris-(hydroxymethyl)aminomethane (HF-TAC). Transfer to HF-TAC maintained the native state of the proteins and prevented their precipitation. Provided the concentration of HF-TAC was high enough, HF-TAC/membrane protein complexes ran as single bands upon centrifugation in sucrose gradients. Bacteriorhodopsin and the cytochrome b 6 f complex, both of which are detergent-sensitive, exhibited increased biochemical stability upon extended storage in the presence of a high concentration of HF-TAC as compared to detergent micelles. The stabilization of cytochrome b 6 f is at least partly due to a better retention of protein-bound lipids. ß

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“…14 Because of the strong hydrophobic (and lipophobic) interactions they develop, fluo rinated Surfactants have a compulsion to collect and organize at interfaces and to collect into discrete supramolecular assemblies when dispersed in water and other solvents. Thus they can be used in lower concentrations, which helps to offset their higher cost.…”

Section: Fluorosurfactants: More Effective Yet Less Hemolyticmentioning

confidence: 99%

Fluorocarbons and Fluorosurfactants for In Vivo Oxygen Transport (Blood Substitutes), Imaging, and Drug Delivery

Riess¹,

Krafft²

1999

MRS Bull.

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The development of biomaterials to treat, repair, or reconstruct the human body is an increasingly important component of materials research. Collaboration between materials researchers and their industrial and clinical partners is essential for the development of this complex field. To demonstrate the importance of these interactions, two articles in this issue focus on advances in biomaterials relating to the use of colloidal systems for transport, drug delivery, and other medical applications. These articles were coordinated by Dominique Muster (Université Louis Pasteur, Strasbourg) and Franz Burny (Hôpital Erasme, Brussels). The following is the first of these two articles.A large variety of colloidal Systems involving highly fluorinated components have been prepared and investigated in recent years. These fluorinated Systems comprise diverse ty pes of emulsions (e.g., direct, reverse, and multiple emulsions; microemulsions; gel emulsions; waterless emulsions) with a fluorocarbon phase (and often a fluorinated Surfactant), and a ränge of self-assemblies (vesicles, tubules, helices, ribbons, etc.) made from fluorinated amphiphiles. Fluorinated Langmuir films and fluorinated black lipid membranes (BLMs) also have been investigated.Research in this area was driven by the potential applications of such materials in medicine and biology. Fluorocarbon-based products are being developed as injectable oxygen carriers (“blood Substitutes”), media for liquid Ventilation, drug delivery Systems, and contrast agents for ultrasound imaging. One such agent has recently been approved for use in Europe and the United States. Several more products are in an advanced stage of clinical evaluation, and others are in various stages of preclinical development. From a more fundamental Standpoint, these materials are being investigated for assessing and understanding the impact that fluorinated components have on the formation, stability, structure, and properties of colloida l Systems in comparison with their hydrocarbon counterparts. The attention given to fluorinated colloids prompted the synthesis of numerous new families of fluorinated amphiphiles, which were to become components of such colloids.

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Micellization and Adsorption of Fluorinated Amphiphiles: Questioning the 1 CF2≈1.5 CH2 Rule

Cited by 65 publications

References 11 publications

A self-assembly toolbox for thiophene-based conjugated polyelectrolytes: surfactants, solvent and copolymerisation

A self-assembly toolbox for thiophene-based conjugated polyelectrolytes: surfactants, solvent and copolymerisation

Hemifluorinated surfactants: a non‐dissociating environment for handling membrane proteins in aqueous solutions?

Fluorocarbons and Fluorosurfactants for In Vivo Oxygen Transport (Blood Substitutes), Imaging, and Drug Delivery

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