Micosis fungoide en niños y adolescentes: descripción de una serie de 23 casos

Ocampo, O.J. Valencia; Julio, L.; Zapata, Vallejo; Correa, Luis Alfonso; Vasco, Carlos Eduardo; Correa, S.; Velásquez‐Lopera, Margarita María

doi:10.1016/j.ad.2019.04.004

Cited by 14 publications

(2 citation statements)

References 25 publications

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“…In the current research, the incidence of mycosis fungoides (MF) was higher in males (60%) (40%) with a male to female ratio equals 3:2 which was matching with Sidiropoulou et al, 2020 [9] , Ocampo et al, 2020 [10] , Amorim et al, 2018 [11] and Boulos et al, 2014 [12] , they had demonstrated that the incidence of MF was higher in males.…”

Section: Discussionsupporting

confidence: 88%

“…The higher incidence of MF in our research was among adults which was in the same line with Alghamdi et al, 2012 [14] , who had concluded that the mean age of their MF patients was 33.5. However, Jung et al, 2021 [15] , Ocampo et al, 2020 [10] , Castano et al, 2013 [16] had observed that the incidence of mycosis fungoides, especially the hypopigmented variant was more common among children and adolescents. On the other hand, Leinweber et al, 2009 [17] , Kuen-kong et al, 2005 [18] had observed that the higher incidence of MF was in older patients, mainly in the fifties.…”

Section: Discussionmentioning

confidence: 99%

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Immunohistochemical research of CADM 1 in mycosis fungoides

Attia¹,

Neinaa²,

Mohamed³

et al. 2023

Int. J. Dermatol. Venereology Leprosy Sci.

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Background: Mycosis fungoides (MF) is the most prevalent form of cutaneous lymphoma, characterised by clonal proliferation of atypical CD4+ T-lymphocytes. Objectives: The goal of this research is to investigate CADM1 antibody expression in skin lesions of MFby immunohistochemistry, to throw a light on its possible role in etiology and worsening of this type of cutaneous lymphoma. Patients and methods: This research was carried out on 20 cases with various stages of mycosis fungoides, specimens were selected from the Outpatient Clinic of Dermatology and Venereology Department, Tanta University Hospitals. 4mm punch skin biopsies were taken and were examined by H&E and CADM1 antibodies. Results: There was statistically significant upregulation of CADM1 expression in MF specimens with statically significant positive correlation between CADM1 expression and progression of mycosis fungoides. Conclusion: CADM1 may be useful as a potential diagnostic marker for mycosis fungoides. Moreover, CADM1 may be of value in assessment of mycosis fungoides progression.

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