Micro Total Analysis System Application for Biomedicals: A Mini-Review

Kurniawan, Yehezkiel Steven; Ding, Mengyao; Song, Guangzhou; Tian, Wei; Li, Helei; Huiuk, Yi; Yin, Yin; Dong, Fenglin; Wang, Jiannan

doi:10.26717/bjstr.2019.12.002294

Cited by 5 publications

(4 citation statements)

References 21 publications

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“…In 2001, Burns and Ramshaw firstly reported that the mass transfer of acetic acid from kerosene to aqueous phase was significantly enhanced by using droplet microfluidic device [33]. As of today, there are many types of microfluidic devices, such as continuous microfluidic devices, droplet microfluidic devices, paper microfluidic devices, and digital microfluidic devices have been fabricated and applied for many applications [34,35]. Each of them serves as a unique platform for certain applications.…”

Section: Droplet Microfluidic Devicementioning

confidence: 99%

Droplet Microfluidic Device for Rapid and Efficient Metals Separation Using Host-Guest Chemistry

Kurniawan¹,

Sathuluri²,

Ohto³

2020

Advances in Microfluidic Technologies for Energy and Environmental Applications

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Metals are pivotal elements in our daily life and industrial processes, to produce electronic devices, catalysts, smart materials and so on. However, they are mostly present as a mixture in the environment that makes their separation challenging over the past decade. Host-guest chemistry principle thoroughly has been used to design and synthesize thousands of organic receptors with high complexation ability and selectivity to certain metal ions. On the other hand, the droplet microfluidic device is well-known for its unique characteristics of fluid dynamics, such as large specific surface area and short diffusion distance making the process robust and efficient. Therefore, many reports of research employ host-guest chemistry of the droplet microfluidic system for the effective metal separation process. This chapter deals with up-to-date examples of the droplet microfluidic system application for separation of base and alkali metals, recovery of rare-earth and precious metals and removal of heavy metals either from the competitive metal system or from the real waste solution sample through solvent extraction techniques utilizing host-guest chemistry principle.

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Section: Droplet Microfluidic Devicementioning

confidence: 99%

Droplet Microfluidic Device for Rapid and Efficient Metals Separation Using Host-Guest Chemistry

Kurniawan¹,

Sathuluri²,

Ohto³

2020

Advances in Microfluidic Technologies for Energy and Environmental Applications

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“…Organ-on-chips culture the biological cells and investigate their compatibility and metabolism directly which is hardly monitored by another experimental setup. Because of that, it is possible now for a real-time monitoring of biomarker labeling, drug's mechanism of action, clinical pathology, tissue, and organ physiology just within a microscale portable device and without any victim animal [106,107]. In addition to that, the microfluidic probe has been also employed for a single-cell pharmacological analysis which is remarkable [108,109].…”

Section: Where Is the Microfluidics Today?mentioning

confidence: 99%

Microfluidics Era in Chemistry Field: A Review

et al. 2019

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By miniaturizing the reactor dimension, microfluidic devices are attracting world attention and starting the microfluidic era, especially in the chemistry field because they offer great advantages such as rapid processes, small amount of the required reagents, low risk, ease and accurate control, portable and possibility of online monitoring. Because of that, microfluidic devices have been massively investigated and applied for the real application of human life. This review summarizes the up-to-date microfluidic research works including continuous-flow, droplet-based, open-system, paper-based and digital microfluidic devices. The brief fabrication technique of those microfluidic devices, as well as their potential application for particles separation, solvent extraction, nanoparticle fabrication, qualitative and quantitative analysis, environmental monitoring, drug delivery, biochemical assay and so on, are discussed. Recent perspectives of the microfluidics as a lab-on-chip or micro total analysis system device and organ-on-chip are also introduced.

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“…In the biomedical field, a micro total analysis system, known as a "lab on a chip", is proposed to reduce space and energy. Such a system is portable and integrates several processes that are performed in the laboratory to analyze and evaluate the samples and miniaturize them into a single device [16,17]. Furthermore, several successful research results have also been presented in the field of robotics based on miniaturized sensors and activators [18,19].…”

Section: Introductionmentioning

confidence: 99%

Miniaturized Distributed Generation for a Micro Smart Grid Simulator

Kim

Lim

2022

Energies

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In this paper, a miniaturization method is proposed for developing micro distributed generation for a micro smart grid simulator. The micro smart grid simulator is a fault simulator that was built to test and verify the new operation control algorithms for smart grids in the laboratory and has a size downscaled to one-thousandth of that of an actual smart grid. The micro distributed generation was designed in a multi-layered structure (dimension: 13 × 20 cm2), in which each function is implemented in several layers, to satisfy the size requirements. Next, the grid synchronization and PQ control algorithms required for the distributed generation were developed. A three-phase 19 V power system was built, and a 19 V–7.5 W three-phase micro distributed generation was realized through experimental verification. In addition, by verifying the effectiveness through grid synchronization and 7.5 W PQ control experiments, it was confirmed that the micro distributed generation based on the proposed miniaturization method can be implemented in a micro smart grid simulator.

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Micro Total Analysis System Application for Biomedicals: A Mini-Review

Cited by 5 publications

References 21 publications

Droplet Microfluidic Device for Rapid and Efficient Metals Separation Using Host-Guest Chemistry

Droplet Microfluidic Device for Rapid and Efficient Metals Separation Using Host-Guest Chemistry

Microfluidics Era in Chemistry Field: A Review

Miniaturized Distributed Generation for a Micro Smart Grid Simulator

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