Microbial Biopolymers and Their Derivatives as Nanotechnological Tools for Medicine

Marcelino, Paulo Ricardo Franco; Gonçalves, Flávio de Oliveira; Aizawa, Nayelen Sayuri; Pereira, Henrique Paiva; Lacerda, Talita M.; Silva, Silvio Silvério

doi:10.1002/9781119769897.ch2

Cited by 2 publications

(1 citation statement)

References 82 publications

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“…Based on their properties, biopolymers from plants, animals, fungi, and bacteria can be used. Due to their biocompatibility, biodegradability, decreased antigenicity, and recyclability, these polymers outperform synthetics in many applications [ 60 ]. Due to their effective antibacterial, anti-inflammatory, and proliferative properties, numerous biopolymers, such as collagen, cellulose, chitosan, alginate, hyaluronan, and carrageenan, have been widely employed for wound healing ( Table 1 ).…”

Section: Biopolymer-based Nanomaterials For Successful Wound Treatmentmentioning

confidence: 99%

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

et al. 2023

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Globally, millions of people suffer from poor wound healing, which is associated with higher mortality rates and higher healthcare costs. There are several factors that can complicate the healing process of wounds, including inadequate conditions for cell migration, proliferation, and angiogenesis, microbial infections, and prolonged inflammatory responses. Current therapeutic methods have not yet been able to resolve several primary problems; therefore, their effectiveness is limited. As a result of their remarkable properties, bio-based materials have been demonstrated to have a significant impact on wound healing in recent years. In the wound microenvironment, bio-based materials can stimulate numerous cellular and molecular processes that may enhance healing by inhibiting the growth of pathogens, preventing inflammation, and stimulating angiogenesis, potentially converting a non-healing environment to an appropriately healing one. The aim of this present review article is to provide an overview of the mechanisms underlying wound healing and its pathophysiology. The development of bio-based nanomaterials for chronic diabetic wounds as well as novel methodologies for stimulating wound healing mechanisms are also discussed.

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Section: Biopolymer-based Nanomaterials For Successful Wound Treatmentmentioning

confidence: 99%

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

et al. 2023

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Nature’s prescription: decoding the power of biopolymers in medical and pharmaceutical applications

Sharma,

Mahajan

2024

Zas Mat

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Over the past few years, the utilization of several biopolymers of natural, synthetic or microbial origin has witnessed a peak in various medical and pharmaceutical applications, like drug delivery, drug formulation, tissue engineering scaffolds, medical implants (e.g., prosthetics, stents), wound healing and dressing materials, and biosensing. This is mainly attributed to their ease of processing, biodegradability, high bioactivity, and biocompatibility compared to synthetic polymers. Moreover, a surge in the development of bio-/nanocomposites has emerged, with an aim to enhance the inherent properties of raw biopolymers derived from natural/microbial sources. This review is mainly focused on the different types of biopolymers or their composites utilized in medicinal or pharmaceutical industries and sheds light on the key advantages and limitations associated with their synthesis or use. Furthermore, the article presents a list of commercialized biopolymer composites with a discussion on the future scope of using these “gifts of nature” in the medical field.

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Microbial Biopolymers and Their Derivatives as Nanotechnological Tools for Medicine

Cited by 2 publications

References 82 publications

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

Nature’s prescription: decoding the power of biopolymers in medical and pharmaceutical applications

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