Microbicide Preference among Young Women in California

Holt, Bethany Young; Morwitz, Vicki G.; Ngo, Long; Harrison, Polly F.; Whaley, Kevin J.; Pettifor, Audrey; Nguyen, Anh H.

doi:10.1089/jwh.2006.15.281

Cited by 43 publications

(57 citation statements)

References 24 publications

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“…However this observation, This study suggests that professionals would support which challenges the widely acknowledged power female-controlled HIV/STI prevention options particularly imbalance with respect to sexual decisions in favor of the the vaginal microbicides, a finding which is similar to earlier 23 12,13, [22][23][24] men, should be interpreted with caution. It is likely that this reports from other parts of the world.…”

Section: Discussionsupporting

confidence: 61%

Acceptability of female-controlled HIV/STI prevention options among professionals in Dhaka, Bangladesh

Ara¹,

Begum²,

Nweneka

2013

SE Asia J. Pub. Health

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Millions of women worldwide lack the power to protect themselves from HIV; current prevention options require cooperation from the male partners. Limited prospects for an HIV vaccine and continued escalation of HIV make female-controlled HIV/STI prevention options like microbicides desirable. While socio-cultural factors could reduce acceptability of these options by vulnerable women, opinion leaders like health personnel and teachers could positively influence their acceptability. The aim of this study was to assess the acceptability of female-controlled HIV/STI prevention options among medical doctors, nurses, pharmacists and secondary school teachers in Dhaka, Bangladesh. A cross-sectional study was conducted using a self-administered semi-structured questionnaire among 375 professionals (nurses, doctors, pharmacists and teachers). The questionnaire assessed the respondents perception of HIV, and their attitudes towards female-controlled HIV/STI prevention options such as female condoms and vaginal microbicides. The study revealed that 98.4% of the respondents were of the opinion that women should determine their HIV/STI prevention options, while 89.3% agreed that options which empower women would be acceptable. It was also found that 18.4% would use the female condoms while 34.4% would use vaginal microbicides. Factors associated with willingness to use the female-controlled prevention options were HIV risk perception, marital status, profession, and duration in profession. There was no association between willingness to use female condoms and willingness to use the vaginal microbicides. While male condom use was positively associated with willingness to use female condom, there was no significant relationship between male condom use and willingness to use the vaginal microbicides. The study showed that professionals strongly supported HIV/STI prevention options that are female-controlled, with most preferring vaginal microbicides to the female condoms. Such support would inform the design of appropriate interventions to prepare the professionals for the eventual advent of an effective microbicide as a HIV/AIDS prevention option.South East Asia J Public Health | Jan-June 2012 | Vol 2 Issue 1 | 46-53 DOI: http://dx.doi.org/10.3329/seajph.v2i1.15265

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Section: Discussionsupporting

confidence: 61%

Acceptability of female-controlled HIV/STI prevention options among professionals in Dhaka, Bangladesh

Ara¹,

Begum²,

Nweneka

2013

SE Asia J. Pub. Health

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“…Also, as in other studies, we found that younger women were more likely to report that side effects would affect their likelihood of using the product. 11,15 Previous research suggests that women may not attempt, may reduce the amount, or may discontinue product use if the microbicide causes irritation, excessive leakage, or wetness. 6 The results also suggest that women who had a greater lifetime number of sex partners were more interested in protection features, although this finding was marginally significant.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5][6][7][8][9][10][11][12][13][14][15] These studies suggest that several factors may influence microbicide acceptability, including a woman's sociodemographic characteristics, personal risk (real or perceived), cultural norms and practices, side effects, and the smell or taste of a product. [3][4][5][6][7][8][9][10][11][12][13][14][15] An increased understanding of which attributes of a microbicide are most appealing to women at increased risk for STDs may help ensure that effective products are used.…”

mentioning

confidence: 99%

Preferred Characteristics of Vaginal Microbicides in Women with Bacterial Vaginosis

Cook

Downs

Marrazzo

et al. 2009

Journal of Women's Health

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Background: Vaginal microbicides have the potential to reduce HIV=STD acquisition when used consistently. Our objectives were to determine product attributes associated with willingness to use a vaginal microbicide and whether product preferences varied according to participant characteristics. Methods: Women (n ¼ 408) with bacterial vaginosis (BV) were recruited as part of a randomized trial to prevent BV. Participants completed a survey interview that assessed demographic information, sexual history, and douching behavior. To assess microbicide preferences, women rated whether specific product attributes would make them more or less likely to use a vaginal microbicide. Principal components analyses revealed two major groupings for the product attribute items. We determined the relative importance of each group of product attributes and whether the importance of the different groupings varied among subgroups of women. Results: The participants' mean age was 24 years (range 14-45), 64% were black, and 74% were unmarried. Overall, participants reported being most likely to use a vaginal product with protection properties (2.54), whereas they were nearly neutral regarding side effects (0.56). The individual product attributes, could prevent BV, could prevent vaginal odor (2.72), and could prevent vaginal itching and burning (2.61), were rated similarly or slightly higher than could reduce the risk of getting an STD (2.58) or could reduce the risk of getting HIV (2.44). In multivariate analyses, protection attributes were rated significantly higher among older women and marginally higher in women with a greater number of lifetime sexual partners. Younger women were most likely to report that side effects would affect their likelihood of using the product. Conclusions: Women with BV rated potential protection features of a vaginal microbicide higher than side effects. A product's personal hygiene aspects were rated equally or more important than the product's ability to prevent HIV=STD infections. Younger women may respond to different factors that influence product acceptability and adherence.

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“…Studies investigating microbicide development and use typically utilize convenience samples recruited via word of mouth, flyers, and outreach, often at a variety of community-based organizations (Coggins et al, 1998;Hammett, et al, 2000a, b;Holt et al, 2006;Mason et al, 2003). Weeks et al (2004) used targeted sampling with outreach and referrals to recruit a sample of women at high risk for HIV infection.…”

Section: Introductionmentioning

confidence: 99%

The Utility of Non-proportional Quota Sampling for Recruiting At-risk Women for Microbicide Research

et al. 2007

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In the context of a measurement development study designed to contextualize microbicide acceptability, a sample that represented a range of at-risk women and maintained the statistical power needed for validity analyses was required. A non-proportional quota sampling strategy focused on race/ethnicity and number of sexual partners was utilized. This strategy resulted in enrollment of approximately equal proportions of Latina (31%), Black (36%), and White (32%) women, and an approximately 1:2 ratio of single-partnered (29%) and multi-partnered (71%) women. About 17% of women screened were ineligible based on eligibility criteria; an additional 16% were ineligible based on quota closures. Most participants were recruited through word of mouth (39%), communitybased organizations (19%), or media sources (19%). Women recruited through word of mouth had the highest screen-to-interview completion percentage (67%). Non-proportional quota sampling is a feasible option for ensuring adequate representation of sample characteristics in microbicide research, but this goal should be weighed against cost and staff burden.

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Microbicide Preference among Young Women in California

Abstract: Our findings help illustrate microbicide product preferences and demand among young women in California, and the methodological approach should lend itself to other populations as well as during clinical trials when understanding product use and nonuse is critical.

Cited by 43 publications

References 24 publications

Acceptability of female-controlled HIV/STI prevention options among professionals in Dhaka, Bangladesh

Acceptability of female-controlled HIV/STI prevention options among professionals in Dhaka, Bangladesh

Preferred Characteristics of Vaginal Microbicides in Women with Bacterial Vaginosis

The Utility of Non-proportional Quota Sampling for Recruiting At-risk Women for Microbicide Research

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