Microbiology of Chronic Suppurative Otitis Media: A Prospective Study in a Tertiary Care Hospital

Balan, Sreeshma; Viswanatha, Borlingegowda

doi:10.15406/joentr.2017.09.00277

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…The results of the current study were in consistence with John et al, (39), Balan and Viswanatha, (40) reported that common fungal agents causing secondary infection in Chronic suppurative otitis media (CSOM) are Candida spp., Aspergillus spp., Rhizopus spp., and Penicillium spp. Previous literature showed that among the fungal isolates, Aspergillus as well as Candida were the most widespread species responsible for otomycosis globally but other causative isolated fungi species have been belonged to genera Penicillium, Fusarium, Mucoraceae, Scopulariopsis, Alternaria, Malassezia in addition to various dermatophytes (41).…”

Section: Discussionsupporting

confidence: 90%

Aspergillus fumigatus identification and antibiotic sensitivity in Iraqi patients

Zainab K Salih,

Abdul Basit A Abdulla,

Israa J Shamkhi

2023

World J. Bio. Pharm. Health Sci.

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Pulmonary aspergillosis is a severe infection in immunocompromised caused by Aspergillus fungi, with Aspergillus fumigatus being the most frequently cultured of this genus, although A. flavus, A. niger, A. terrus also include If left untreated, invasive aspergillosis can have mortality approaching 100%. A total of 105 samples were collected from TB patients with symptom of lung infection . These sputum samples were obtained from patients treated in Public health department Chest and Respiratory diseases clinic, from February 2023 to April 2023. All samples were transferred to the laboratory for culturing to isolation and identification fungi after labeling each sample with questionnaire form. Lacto phenol cotton blue staining method was used in identification of fungal isolates, fungi isolated by inoculating sample on culture media such as sabouraud dextrose agar (SDA), and disc diffusion. The sample mean ± standard deviasion (SD) of age was 48.5±14.2 years (ranged 9-75 years). Male to female ratio was 2:1.5, age groups number and percentage were 32(30.5%), 13(12.4%), 14(13.3%), 14(13.3%), 16(15.2%) and 16(15.3%) in the age groups <=29, 30-39, 40-49, 50-59, 60-69 and >=70. Laboratory investigations indicated that 40 (38.1%) of the total samples diagnosed with a fungus species, 16 (15.3%) of them present with Candida species followed by 14 (13.3%) with A.fumigatus, 5 (4.8%) with A. niger, 3 (2.8%) with A.terreus and 2 (1.9%) A.flavus, while negative results were indicated in 65 (61.9%) of collected samples. A.fumigatus. isolates were subjected to susceptibility testing using different antifungals. The antifungal drugs NYS, KEA, CMZ, ICZ and PCZ were the most effect. Resistant outcomes were reported in FCZ, while intermediate results were showed in MIC and AMB. The results showed an increase in the prevalence of Aspergillus fumigatus in Iraqi patients. This prevalence may be alarming on public health.

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Section: Discussionsupporting

confidence: 90%

Aspergillus fumigatus identification and antibiotic sensitivity in Iraqi patients

Zainab K Salih,

Abdul Basit A Abdulla,

Israa J Shamkhi

2023

World J. Bio. Pharm. Health Sci.

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“…Chronic suppurative otitis media has a significant impact on hearing loss and can cause complications if not treated appropriately 9 . The use of antibiotics has reduced the incidence of CSOM complications, but the use of antibiotics incorrectly leads to germ resistance 9,10 . Therapy CSOM is a challenge in itself because the disease tends to recur easily, and the germs can quickly turn resistant.…”

Section: Israa Hussein Hamzah Noor Al-huda Ali a H Saeed Alaa N Moham...mentioning

confidence: 99%

“…The patterns of germs and antibiotic sensitivity in CSOM patients differ from one place to another 9,11,12 . Understanding germs' pattern and their antibiotic sensitivity will lead to a rational choice of antibiotics to prevent the emergence of resistance 9,10 . This study aims to report the microbiological profile and antibiotic sensitivity patterns in CSOM patients.…”

Section: Israa Hussein Hamzah Noor Al-huda Ali a H Saeed Alaa N Moham...mentioning

confidence: 99%

Microbiological profile with Antibiotic Sensitivity Pattern for Chronic Suppurative Otitis Media in A Tertiary Hospital, Indonesia

Artono

Surayya

Purnami

et al. 2022

RJPT

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Introduction: Chronic suppurative otitis media (CSOM) is a chronic inflammation in the middle ear and mastoid space that repeatedly secretes through the perforated membrane of tympanic disease over three months. This disease is a critical cause of hearing in developing countries. The prevalence of CSOM in Indonesia is 3.8%. Improper use of antibiotics leads to germicidal incidence. Understanding the pattern of germs and their antibiotic sensitivity will lead to a rational choice of antibiotics to prevent the emergence of resistance. Aim: to report the microbiological profile and sensitivity patterns in CSOM patients in our department. Materials and Methods: This is a retrospective descriptive study conducted on 45 patients from September 2019 - March 2020 at the ENT-KL Department of Dr Soetomo Surabaya Indonesia. Forty-five samples were collected from CSOM patients who underwent mastoidectomy. Specimens were collected from these patients, examination, isolation, examination and isolation antibiogram were carried out according to standard procedures. Results: A total of 45 samples were obtained from this study, and all (57.77%) of the patients were identified as CSOM cases with cholesteatoma. The number of women is 62.3% more than men, and the age group 12 to 16 (20.0%) is the most reported. There were 75.6% perforations in the tympanic membrane, and a central perforation was primarily found (35.6%). Most of the Schuller mastoid X-ray results showed sclerotic features in 29 patients (59.2%). Of the 45 ear swabs, about 68.89% of the surgical materials gave positive culture results, the remaining 31.11%. There was no microbial growth, where most of the growth of monomicrobial bacteria (57.8%). Of the isolates that grew, 70.58% were identified as the group of gram-negative bacteria, with Pseudomonas Aerogenosa isolates being the most common (44.11%). Conclusion: The sensitivity test showed the most sensitivity to Meropenam, Amikacin, Piperacillin-Tazobactam, Ceftasidim and Cefoperazone-Sulbactam Cefotaxime and Ceftriaxone showed lower sensitivity.

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“…Two prominent GC bacteria that are often co-isolated from chronic infections are Pseudomonas aeruginosa and Staphylococcus aureus. They have been isolated from chronic infections like chronic wounds ( Gjødsbøl et al., 2006 ), pulmonary cystic fibrosis ( Henson et al., 2019 ), chronic osteomyelitis ( Masters et al., 2022 ), and chronic otitis media ( Viswanatha, 2017 ). The dyad, therefore, is of immense interest to researchers studying chronic polymicrobial infections.…”

Section: Introductionmentioning

confidence: 99%

Solving polymicrobial puzzles: evolutionary dynamics and future directions

Srinivasan,

Sajeevan,

Rajaramon

et al. 2023

Front. Cell. Infect. Microbiol.

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Polymicrobial infections include various microorganisms, often necessitating different treatment methods than a monomicrobial infection. Scientists have been puzzled by the complex interactions within these communities for generations. The presence of specific microorganisms warrants a chronic infection and impacts crucial factors such as virulence and antibiotic susceptibility. Game theory is valuable for scenarios involving multiple decision-makers, but its relevance to polymicrobial infections is limited. Eco-evolutionary dynamics introduce causation for multiple proteomic interactions like metabolic syntropy and niche segregation. The review culminates both these giants to form evolutionary dynamics (ED). There is a significant amount of literature on inter-bacterial interactions that remain unsynchronised. Such raw data can only be moulded by analysing the ED involved. The review culminates the inter-bacterial interactions in multiple clinically relevant polymicrobial infections like chronic wounds, CAUTI, otitis media and dental carries. The data is further moulded with ED to analyse the niche colonisation of two notoriously competitive bacteria: S.aureus and P.aeruginosa. The review attempts to develop a future trajectory for polymicrobial research by following recent innovative strategies incorporating ED to curb polymicrobial infections.

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Microbiology of Chronic Suppurative Otitis Media: A Prospective Study in a Tertiary Care Hospital

Cited by 5 publications

References 7 publications

Aspergillus fumigatus identification and antibiotic sensitivity in Iraqi patients

Aspergillus fumigatus identification and antibiotic sensitivity in Iraqi patients

Microbiological profile with Antibiotic Sensitivity Pattern for Chronic Suppurative Otitis Media in A Tertiary Hospital, Indonesia

Solving polymicrobial puzzles: evolutionary dynamics and future directions

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