MicroCantilever (MC) based nanomechanical sensor for detection of molecular interactions

Mechanism governing surface stress generation

“…In all mathematical and experimental studies mentioned above, the same mechanism for the sensing was assumed: the cantilever surface was covered with receptor species that could combine with ligand molecules in the solution and cause cantilever bending. Kang et al [18] called this sensing method as conventional or direct mode of sensing and found some limitation in sensing with this method especially when the concentration of ligand molecules in the solution were so low. He proposed an alternative method of sensing called competition mode of sensing.…”