Microchemomechanical Systems

Randhawa, Jatinder S.; Laflin, Kate E.; Seelam, Natasha; Gracias, David H.

doi:10.1002/adfm.201100482

Cited by 59 publications

(44 citation statements)

References 117 publications

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“…It is important to note that in this kind of actuation, chemical conformation plays a significant role, responding to various stimuli such as redox potentials, proteins and charge grouping on single polymer chains [30]. Randhawa et al [48] reviewed some of the advances and their implications for the development of different bio-inspired autonomous chemical actuation mechanisms. As the most versatile category of actuation systems, some prototypes and applications are microgrippers, microcages, internal combustion engines, chemical batteries, artificial muscles and drug delivery systems [13,[48][49][50].…”

Section: Bio/chemical Actuation Mechanismsmentioning

confidence: 99%

Switchable molecule-based materials for micro- and nanoscale actuating applications: Achievements and prospects

Manrique-Juárez

Rat

Salmon

et al. 2016

Coordination Chemistry Reviews

229

202

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Section: Bio/chemical Actuation Mechanismsmentioning

confidence: 99%

Switchable molecule-based materials for micro- and nanoscale actuating applications: Achievements and prospects

Manrique-Juárez

Rat

Salmon

et al. 2016

Coordination Chemistry Reviews

229

202

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“…Selffolding stimuli-responsive soft robots can regulate their grasping configuration by converting environmental signals into mechanical ones. Because of this, they have been successfully utilized in a vast range of applications, such as drug delivery, diagnostics, and tissue engineering [6], [7].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of an electromagnetic system with haptic feedback for control of untethered, soft grippers affected by disturbances

Ongaro

Pacchierotti

Yoon

et al. 2016

2016 6th IEEE International Conference on Biomedical Robotics and Biomechatronics (BioRob)

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Abstract-Current wireless, small-scale robots have restricted manipulation capabilities, and limited intuitive tools to control their motion. This paper presents a novel teleoperation system with haptic feedback for the control of untethered soft grippers. The system is able to move and open/close the grippers by regulating the magnetic field and temperature in the workspace. Users can intuitively control the grippers using a grounded haptic interface, that is also capable of providing compelling force feedback information as the gripper interacts with the environment. The magnetic closed-loop control algorithm is designed starting from a Finite Element Model analysis. The electromagnetic model used is validated by a measurement of the magnetic field with a resolution of 0.1 mT and sampling rate of 6.8×10 6 samples/m 2 . The system shows an accuracy in positioning the gripper of 0.08 mm at a velocity of 0.81 mm/s. The robustness of the control and tracking algorithms are tested by spraying the workspace with water drops that cause glares and related disturbances of up to 0.41 mm.

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“…This approach required the creation of elastomeric sheets patterned with magnetic dipoles; self-folding was driven by the interplay between the elastic bending energy and the magnetic energy. Similarly, Randhawa et al ., have described the concept of microchemomechanical systems (MCMS) which incorporate polymeric triggers on pre-stressed metallic thin films to achieve chemical stimuli-responsive gripping devices [80]. These devices include wireless surgical grippers those that fold (close) and un-fold (open) on exposure to enzymes such as trypsin and cellulase [33, 34].…”

Section: Self-folding Of Polymeric Containersmentioning

confidence: 99%

Self-folding polymeric containers for encapsulation and delivery of drugs

Fernandes

Gracias

2012

Advanced Drug Delivery Reviews

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258

182

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Self-folding broadly refers to self-assembly processes wherein thin films or interconnected planar templates curve, roll-up or fold into three dimensional (3D) structures such as cylindrical tubes, spirals, corrugated sheets or polyhedra. The process has been demonstrated with metallic, semiconducting and polymeric films and has been used to curve tubes with diameters as small as 2 nm and fold polyhedra as small as 100 nm, with a surface patterning resolution of 15 nm. Self-folding methods are important for drug delivery applications since they provide a means to realize 3D, biocompatible, all-polymeric containers with well-tailored composition, size, shape, wall thickness, porosity, surface patterns and chemistry. Self-folding is also a highly parallel process, and it is possible to encapsulate or self-load therapeutic cargo during assembly. A variety of therapeutic cargos such as small molecules, peptides, proteins, bacteria, fungi and mammalian cells have been encapsulated in self-folded polymeric containers. In this review, we focus on self-folding of all-polymeric containers. We discuss the mechanistic aspects of self-folding of polymeric containers driven by differential stresses or surface tension forces, the applications of self-folding polymers in drug delivery and we outline future challenges.

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Microchemomechanical Systems

Cited by 59 publications

References 117 publications

Switchable molecule-based materials for micro- and nanoscale actuating applications: Achievements and prospects

Switchable molecule-based materials for micro- and nanoscale actuating applications: Achievements and prospects

Evaluation of an electromagnetic system with haptic feedback for control of untethered, soft grippers affected by disturbances

Self-folding polymeric containers for encapsulation and delivery of drugs

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