2010
DOI: 10.1007/s10544-010-9396-3
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Microdialysis based device for continuous extravascular monitoring of blood glucose

Abstract: Glycemic control of intensive care patients can be beneficial for this patient group but the continuous determination of their glucose concentration is challenging. Current continuous glucose monitoring systems based on the measurement of interstitial fluid glucose concentration struggle with sensitivity losses, resulting from biofouling or inflammation reactions. Their use as decision support systems for the therapeutic treatment is moreover hampered by physiological time delays as well as gradients in glucos… Show more

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Cited by 12 publications
(5 citation statements)
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“…Some pores may also be clogged with particulates or wax (used for wafer-mounting during back-side etching). Changes in probe processing or modifying surfaces may prove useful to improve recovery. , …”
Section: Resultsmentioning
confidence: 99%
“…Some pores may also be clogged with particulates or wax (used for wafer-mounting during back-side etching). Changes in probe processing or modifying surfaces may prove useful to improve recovery. , …”
Section: Resultsmentioning
confidence: 99%
“…4 For intensive care units, different approaches have been chosen, using either subcutaneously implanted microdialysis catheters, intravascularly inserted probes or extracorporeal microdialysis with continuously sampled and heparinised whole blood, from which dialysates have been obtained. [5][6][7][8][9][10][11] The latter microdialysis technique, as described in detail by Feichtner et al,7 has also been used by us in combination with infrared spectroscopy for ex-vivo glucose quantification. 12,13 Recently, an overview for continuous glucose monitoring (CGM) systems, based on electrochemical sensing as utilised in needle-type sensors directly implanted and micro-dialysis based systems for interstitial fluid or intravascular application with ex-vivo detection, has been given by Lucarelli et al 14 .…”
Section: Introductionmentioning
confidence: 99%
“…Dachao Li 1 , Qingmei Xu 1 , Yu Liu 1 , Ridong Wang 1 , Kexin Xu 1 and Haixia Yu 1,2 glucose concentrations in interstitial fluid [11]. However, the standard for continuous glucose monitoring in clinical practice is still blood glucose concentration at present [12].…”
Section: A High-accuracy Measurement Methods Of Glucose Concentration...mentioning
confidence: 99%