Microfluidic fabrication of X-ray-visible sodium hyaluronate microspheres for embolization

Abstract

Bi2S3@SH-1 microspheres are fabricated by single-step microfluidics, have good biocompatibility, mechanical properties, certain X-ray visibility, and excellent embolization effects, which hold great potential for embolotherapy application.

Development and evaluation of polyacrylamide microspheres loaded with phloretin and tantalum for transcatheter arterial embolization

“…Currently, there has been an attempt to incorporate several contrast agents into microspheres for X-ray visualisation purposes, including bismuth sulde, barium salts, and tantalum. [13][14][15][16] Among the aforementioned, tantalum nanoparticles are recognised as a promising X-ray contrast agent with excellent X-ray blocking effect and chemical stability. Moreover, they possess good biocompatibility and do not cause signicant adverse reactions, making them highly suitable as contrast agents for microsphere preparations.…”