Microfluidics-based microwave sensor

Dai, Li; Zhao, Xue; Jie, Guo; Feng, Shilun; Kang, Yuejun

doi:10.1016/j.sna.2020.111910

Cited by 44 publications

(16 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Especially, the Fenton reagents constantly induced the Fe 2+ into the reaction are nontoxic with trace dosage about dozens of microliters, which indicates the less reagent consumption and the released effluent liquor disposal. Though the completed digestion of total phosphorus was not realized in this work, the flow rate and the setup would be further optimized, and the oxidation pathway would be enhanced by inducing some other advanced oxidation pathway, such as the electrical field forcing the separation of electrons and holes, 29 the microwave oxidation, 30 and so on. Or even the original water sample with high content of phosphorus can be diluted first by adding the dilution cell before the digestion cell.…”

Section: Resultsmentioning

confidence: 99%

Optofluidic Platform for Rapid On-Chip Analysis of Total Phosphorus in Surface Water Using Absorption Spectrometry

et al. 2022

View full text Add to dashboard Cite

Optofluidic devices are of high interest for online monitoring and analyzing biochemical targets in water by integrating the complex on-chip pretreatment of target analytes and spectral analysis. Compared with the traditional bulk equipment, versatile optical detection and biochemical analysis are more easily integrated on an optofluidic chip, which promotes the development of on-chip real-time rapid detection and monitoring. Here, we report an optofluidic platform for online monitoring total phosphorous in water by absorption spectrometry, which naturally combines the merits of both the photo-Fenton effect and microfluidics to realize the rapid on-chip digestion of phosphate at room temperature and normal pressure. The functional cells for chromogenic reaction and optical absorption detection are respectively fabricated on the platform to analyze the content of total phosphorus in surface water. In the experiment, the on-chip digestion time of phosphate is dramatically declined to 8.6 seconds and thus the detection time is greatly shortened to a few minutes. The detection range of total phosphorus is demonstrated as 0.005–1.00 mg/L, which satisfies the detection requirements of most environmental water samples. Its availability for measuring the total phosphorous in real water samples is also verified. Predictably, this platform is adapted to on-chip analyze many other biochemical targets in water.

show abstract

Section: Resultsmentioning

confidence: 99%

Optofluidic Platform for Rapid On-Chip Analysis of Total Phosphorus in Surface Water Using Absorption Spectrometry

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Microfluidic technology revolutionizes the method for sampling, sample separation, mixing, chemical reaction, and electrochemical detection in one device. Such technology is beneficial for real-time detection, enabling multiplexing, and assembling multiple microfluidic components [ 76 , 181 ]. The use of microfluidic technology in an electrochemical sensing platform can significantly minimize the volume of samples as it can process a small volume of fluids by using tiny channels with dimensions at the microscale, usually tens to hundreds of micrometers [ 182 ].…”

Section: The Advanced Electrochemical Sensing Technologies For Point-...mentioning

confidence: 99%

“…The advancement in microfluidic technologies allows the integration of smart solutions such as the Internet of Medical Things (IoMT), e-health, artificial intelligence (AI), and machine learning to develop innovative healthcare technologies [ 186 , 187 ]. The microfluidic devices can be fabricated using various material bases such as polytetrafluoroethylene (PTFE), polydimethylsiloxane (PDMS), polycarbonate, silicon, glass, quartz, polymethyl methacrylate (PMMA), paper, hydrogel, three-dimensional (3D) printing and thermoset materials that subsequently offer diversity in their development [ 76 , 181 , 188 ].…”

Section: The Advanced Electrochemical Sensing Technologies For Point-...mentioning

confidence: 99%

Utilizing Electrochemical-Based Sensing Approaches for the Detection of SARS-CoV-2 in Clinical Samples: A Review

et al. 2022

View full text Add to dashboard Cite

The development of precise and efficient diagnostic tools enables early treatment and proper isolation of infected individuals, hence limiting the spread of coronavirus disease 2019 (COVID-19). The standard diagnostic tests used by healthcare workers to diagnose severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection have some limitations, including longer detection time, the need for qualified individuals, and the use of sophisticated bench-top equipment, which limit their use for rapid SARS-CoV-2 assessment. Advances in sensor technology have renewed the interest in electrochemical biosensors miniaturization, which provide improved diagnostic qualities such as rapid response, simplicity of operation, portability, and readiness for on-site screening of infection. This review gives a condensed overview of the current electrochemical sensing platform strategies for SARS-CoV-2 detection in clinical samples. The fundamentals of fabricating electrochemical biosensors, such as the chosen electrode materials, electrochemical transducing techniques, and sensitive biorecognition molecules, are thoroughly discussed in this paper. Furthermore, we summarised electrochemical biosensors detection strategies and their analytical performance on diverse clinical samples, including saliva, blood, and nasopharyngeal swab. Finally, we address the employment of miniaturized electrochemical biosensors integrated with microfluidic technology in viral electrochemical biosensors, emphasizing its potential for on-site diagnostics applications.

show abstract

“…Moreover, microfluidic technologies allow the integration of smart solutions such as e-health, the Internet of Medical Things (IoMT), artificial intelligence, and machine learning for developing innovative healthcare technologies [16,17]. Microfluidic technologies enable economic, fast, portable, and sensitive analysis opportunities, and offer versatility in development as the fabrication can be achieved with different material bases such as poly(dimethylsiloxane) (PDMS), poly(methyl methacrylate) (PMMA), polycarbonate, glass, paper, hydrogel, polytetrafluoroethylene (PTFE), thermoset materials, threedimensional (3D) printing materials, and silicon [12,[18][19][20]. Microfluidic systems can be used for real-time sensing and monitoring, can work with small sample and reagent volumes, can allow multiplexing, and can be assembled into multiple microfluidic components [18,19].…”

Section: Introductionmentioning

confidence: 99%

“…Microfluidic technologies enable economic, fast, portable, and sensitive analysis opportunities, and offer versatility in development as the fabrication can be achieved with different material bases such as poly(dimethylsiloxane) (PDMS), poly(methyl methacrylate) (PMMA), polycarbonate, glass, paper, hydrogel, polytetrafluoroethylene (PTFE), thermoset materials, threedimensional (3D) printing materials, and silicon [12,[18][19][20]. Microfluidic systems can be used for real-time sensing and monitoring, can work with small sample and reagent volumes, can allow multiplexing, and can be assembled into multiple microfluidic components [18,19]. Therefore, those systems emerge as a great alternative to commercial detection and imaging systems.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic-based virus detection methods for respiratory diseases

et al. 2021

View full text Add to dashboard Cite

With the recent SARS-CoV-2 outbreak, the importance of rapid and direct detection of respiratory disease viruses has been well recognized. The detection of these viruses with novel technologies is vital in timely prevention and treatment strategies for epidemics and pandemics. Respiratory viruses can be detected from saliva, swab samples, nasal fluid, and blood, and collected samples can be analyzed by various techniques. Conventional methods for virus detection are based on techniques relying on cell culture, antigen-antibody interactions, and nucleic acids. However, these methods require trained personnel as well as expensive equipment. Microfluidic technologies, on the other hand, are one of the most accurate and specific methods to directly detect respiratory tract viruses. During viral infections, the production of detectable amounts of relevant antibodies takes a few days to weeks, hampering the aim of prevention. Alternatively, nucleic acid–based methods can directly detect the virus-specific RNA or DNA region, even before the immune response. There are numerous methods to detect respiratory viruses, but direct detection techniques have higher specificity and sensitivity than other techniques. This review aims to summarize the methods and technologies developed for microfluidic-based direct detection of viruses that cause respiratory infection using different detection techniques. Microfluidics enables the use of minimal sample volumes and thereby leading to a time, cost, and labor effective operation. Microfluidic-based detection technologies provide affordable, portable, rapid, and sensitive analysis of intact virus or virus genetic material, which is very important in pandemic and epidemic events to control outbreaks with an effective diagnosis.

show abstract

Microfluidics-based microwave sensor

Cited by 44 publications

References 63 publications

Optofluidic Platform for Rapid On-Chip Analysis of Total Phosphorus in Surface Water Using Absorption Spectrometry

Optofluidic Platform for Rapid On-Chip Analysis of Total Phosphorus in Surface Water Using Absorption Spectrometry

Utilizing Electrochemical-Based Sensing Approaches for the Detection of SARS-CoV-2 in Clinical Samples: A Review

Microfluidic-based virus detection methods for respiratory diseases

Contact Info

Product

Resources

About